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Home arrow Health arrow Gut Health arrow ZuPoo Review: Is It Really a Gut Health Game-Changer?

ZuPoo Review: Is It Really a Gut Health Game-Changer?

Written by Edibel Quintero, RD
Fact checked by Rosmy Barrios, MD
Last update: September 21, 2023
14 min read 1967 Views 0 Reviews
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Could ZuPoo supplement by UMZU be the answer to enhanced gut health? Find it out in my detailed review of this product, including its pros and cons, and make an informed decision.

zuPoo reviews

How do we vet brands and products? Learn more.

Millions of people around the world are affected by some sort of digestive issues, like intestinal cramping, chronic constipation, or stomach pain. While it’s possible to improve your gut health by making lifestyle and diet changes, adding a supplement to your routine can also help.

However, choosing the right supplement for colon cleansing and improving gut health can be a challenging task. That’s because the market is filled with all types of products, and all of them claim to be the best.

One of the most popular supplements on the market today is ZuPoo. I’ve heard a lot of good things about this product, which made me extremely curious. So, I decided to examine it and give my opinion on whether it actually works or not.

In this review, I’ll share everything I learned about the ZuPoo supplement, including its ingredients, benefits, and potential side effects.

What Is ZuPoo?

Our rating:
  • Clears out the colon
  • Reduces gastrointestinal ailments
  • Supports gut health
Visit ZuPoo
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    Contains natural laxatives that can treat constipation
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    May improve digestive health
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    60-day money-back guarantee
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    More expensive than many other gut health supplements
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    A range of potentially adverse side effects
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    Contains controversial ingredients
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    An unsustainable weight-loss method

ZuPoo is a dietary supplement designed to act as a colon cleanser to flush toxins, eliminate waste, and support a healthy, happy gut. It is created by UMZU, which is a US company that focuses on supplements for hormonal health.

The ZuPoo formula provides a laxative effect that can give relief from constipation. It’s claimed that it cleans out the digestive tract, improves overall digestive health, and even supports weight loss. 

Just like many other dietary supplements, ZuPoo also comes in capsule form. What I liked the most about this product is that its cleansing formula is made from natural ingredients.

Two of the significant ingredients it contains include cascara sagrada and senna leaf powder, which are known to have laxative properties.

⭐ Rating


🍎 Vegan?


🔔 Key ingredients

Senna leaf powder, fennel seed powder, bentonite clay

💰 Price

From $25.46

🔔 Where to buy

How to Use ZuPoo?

Another thing that I liked about the ZuPoo supplement is that it’s pretty easy to use. The company recommends taking 1–2 capsules with a full glass of water before bed.

It’s important to note that the instructions also suggest that you should drink plenty of water throughout the rest of the day when using this supplement. I can tell you that it makes sense because a dietary supplement can make your gut absorb more water.

So, you should definitely increase your water intake when taking ZuPoo or any similar supplement.

Next, it’s a waiting game, and it’s possible to experience a buildup of gas within 12–24 hours after taking the supplement for the first time. Eventually, you can expect bowel movements within 12–48 hours.

According to UMZU, you’ll need to take the ZuPoo supplement for 7 days consecutively to experience a complete flush of the digestive system. The brand also recommends not to take this supplement for more than one full cleanse per 4–6 weeks.

It seems fair, as regular colon cleansing is unnecessary and can be harmful. Generally, the digestive system can remove toxic waste naturally with a healthy diet and plenty of water.

Is ZuPoo Safe to Use?

In my opinion, there’s no single-word answer to this question because everybody reacts differently to such supplementation. But as with any laxative supplement, you should be cautious, as they can cause diarrhea, abdominal cramping, vomiting, and nausea if consumed excessively.

Laxative abuse and misuse can also lead to life-threatening complications like severe dehydration and an electrolyte imbalance. Additionally, these supplements aren’t suitable for people with existing stomach problems as well, and there’s also no scientific research to suggest that ZuPoo is safe for pregnant and breastfeeding women.

While ZuPoo might be safe for most people, it contains some ingredients that can cause negative health effects. For example, long-term use of senna and cascara sagrada is associated with liver damage. So, you must consult with your doctor before taking this product.

Does ZuPoo Really Work?

The ZuPoo supplement contains a blend of plant ingredients, herbs, and barks. After assessing the ingredients, particularly those that work as natural laxatives, I can safely say that ZuPoo does have what it takes to be a potent laxative.

The formula of the supplement does what it’s primarily supposed to: flush waste from your system. It means that it can help you minimize the symptoms of constipation and promote regular bowel movements. I’ve also read many online ZuPoo reviews that support this claim.

Other than these benefits, the company claims that this supplement can also help you with weight loss. However, the ingredients it contains don’t appear to provide this benefit, at least directly. So, if losing weight is your biggest concern, you might want to adjust your diet or exercise routine or look for fiber supplements specially designed for this purpose.

While emptying the colon may make you feel lighter and even lose a few pounds, the result is likely to be temporary. When normal digestion resumes, you can expect to regain the lost weight, as ZuPoo does not contribute to fat loss. Therefore, it’s not the best option for losing a few pounds.

You should use it as a solution to deal with irregular bowel movements rather than an everyday addition to your diet. Thus, ZuPoo appears to have limited health benefits compared with other gut supplements that provide better long-term support for your digestive system.

Key Ingredients of ZuPoo

As mentioned already, ZuPoo Colon Cleanse comes with a blended mixture of plant ingredients, herbs, and barks. Let me explain all the main ingredients in detail.

Key Ingredients of ZuPoo

#1 Cascara sagrada bark extract

Cascara sagrada is a potent laxative ingredient. It contains anthraquinones, organic compounds which stimulate the intestines, allowing waste to pass quickly through the gut.

However, using this ingredient consecutively for more than a week or two can lead to serious side effects. Some of the major ones include dehydration, rapid loss of electrolytes, and muscle weakness.

Therefore, I do not recommend taking this supplement daily for over a week.

#2 Senna leaf powder

Senna is another ingredient in the ZuPoo supplement that has powerful laxative effects. It softens the stool, allowing it to pass more easily through the gut.

Although most people don’t experience any health issues after consuming this ingredient, some can suffer from digestive distress, notably diarrhea and abdominal cramping.

Additionally, it’s also important to note that you shouldn’t consume senna daily because it can have detrimental effects on your gut health. Long-term use can cause laxative dependence and prevent the bowels from functioning as normal on their own.

According to research, this ingredient may be unsafe for people if taken for more than a week without medical advice. That’s why UMZU recommends that users take the ZuPoo supplement for 7 days.

Important Note: ZuPoo is a quick fix for emergency situations only. If you’re having digestion trouble on a regular basis, you should consider looking at fiber supplements to help maintain regular bowel movements.

#3 Fennel seed powder

Fennel is used in traditional medicine for various digestive issues as it may help relax the muscles of the gastrointestinal system.

The seeds of this plant are anti-inflammatory and can help aid indigestion, constipation, gas, and bloating. They are also rich in fiber, which also contributes to good digestion.

#4 Bentonite clay

Bentonite clay has antibacterial and anti-inflammatory properties, and it’s associated with minimizing the symptoms of diarrhea, including food poisoning, mucous colitis, spastic colitis, food allergy, and virus infection.

Clay is often added to colon cleanse products to help remove toxins within the body. As it can stick to toxins, it can help regulate digestion, but further medical research is required.

#5 Cayenne pepper extract

Cayenne pepper has several health benefits, one of which is that it improves digestion by increasing enzyme production in the stomach, which helps the body break down food. The spice may also boost the good bacteria in the gut.

#6 Aloe ferox

Aloe ferox is another ingredient used in the ZuPoo supplement. According to a study, it has detoxifying and laxative properties, which can also help you with losing weight.

However, the study also shows that taking this supplement can also lead to several side effects, such as kidney disease, potassium depletion, abdominal cramps and pain, and diarrhea.

Other ingredients

Other ingredients in the ZuPoo supplement include milk thistle, slippery elm extract, and burdock root powder. Milk thistle is traditionally used as an herbal remedy to support liver health.

Additionally, slippery elm extract contains antioxidants that may protect from inflammation in the intestines, while burdock root can improve digestion.

A Word From Our MD

Expert image border HR_author_photo_Rosmy
Rosmy Barrios
Medical advisor for Health Reporter

Laxatives are a popular medical choice that can immediately relieve constipation and abdominal discomfort. Herbal formulas with natural ingredients can be purchased over the counter, allowing you to manage your digestive health quickly.

However, most laxatives, including ZuPoo, are intended for short-term use. Misusing them does more harm than good and can lead to various health problems.

If you often experience constipation, pay attention to your lifestyle and diet. That’s because the digestive system benefits significantly from healthy habits, like drinking an adequate amount of water, eating a balanced, fiber-rich diet, and exercising regularly.

Lastly, make sure that you consult with your doctor before taking any type of supplement to make sure that you reap the benefits it offers.

Benefits of ZuPoo

Now, let’s talk about all the potential benefits that the ZuPoo supplement offers.

#1 Colon cleansing

ZuPoo is specially designed to work as a colon cleanse supplement, which means it can help flush toxins and waste from the digestive tract.

The two main ingredients used to formulate this supplement are cascara sagrada and senna leaf powder, both of which are well-known for their proven laxative properties.

They can improve your bowel movement and lead to a cleaner and healthier colon, promoting better gut health.

#2 Relief from constipation

The natural laxative properties of ZuPoo’s ingredients, especially senna leaf powder, can soften the stool, as I’ve mentioned above. It allows the waste material to pass through the gut more easily, which can provide relief from constipation.

#3 Potential weight loss support

The company claims that ZuPoo can also help with weight loss. While not directly contributing to fat loss, the temporary weight loss after colon cleansing can make you feel lighter.

However, it’s important to note that ZuPoo’s primary focus is on colon cleansing and gut health, not long-term weight management.

Also, you may regain the weight you lost once you stop taking the supplement and normal digestion resumes.

#4 Natural ingredients

ZuPoo’s formula is made from natural ingredients, and it can be a preferred choice for individuals looking for a more organic approach to gut health.

But it’s worth noting that even natural substances used in this supplement can have potential side effects when used inappropriately or excessively.

#5 Potentially boosts immunity

If you don’t already know, 70–80% of your immune system is in your gut. Since ZuPoo is a colon-cleansing supplement with positive effects on gut health, it’s said that it might also boost immunity.

However, more scientific research is needed to establish any direct link between colon cleansing and immune system enhancement.

#6 Money-back guarantee

While this benefit is not related to your health, it can come in handy for people on a budget. UMZU offers a 60-day money-back guarantee on your first purchase to protect your investments.

However, the company also states that you should use it for at least 2 weeks from the time of shipment.

Cons and Side Effects of ZuPoo

Here are the cons and side effects of ZuPoo Colon Cleanse that I noticed its users experience.

#1 Buildup of gas

It’s possible to experience a buildup of gas within the first 12–24 hours after taking the supplement. This is a common side effect as the colon cleanse process begins.

#2 Controversial ingredients

Some ingredients in ZuPoo, such as cascara and senna, are controversial due to their potential side effects. As I’ve stated earlier, prolonged use of these laxative ingredients can cause nasty side effects.

Some of the common side effects include irregular heartbeat, muscle cramps, urine discoloration, diarrhea, and stomach cramps. If you fail to consume plenty of water after consuming these ingredients, you can fall victim to dehydration and low levels of electrolytes.

Additionally, both cascara and senna are linked to liver damage as well when consumed excessively or long-term. That’s why you should be cautious when consuming these ingredients.

If you experience any unwanted side effects while using ZuPoo, you must stop taking the supplement and seek medical advice from your healthcare professional immediately.

#3 No results at all

As discussed above, the effects of supplements can vary from person to person. However, they should do something to your body when you’re consuming them. But in some instances, it doesn’t seem to be the case with ZuPoo.

I’ve read multiple online reviews where people are expressing their dissatisfaction with ZuPoo, stating that it didn’t make any difference at all for them. I felt it was important to mention this, as it’s something you should keep in mind.

#4 Expensive

I have to say that ZuPoo is a pretty expensive product compared to most dietary supplements. If you buy it from the official website, then a single-day dosage will cost you $2.29.

While you can save some bucks by signing up for a monthly subscription, it won’t be a suitable choice because it’s a laxative supplement and is not intended for long-term daily use. So, in my opinion, the monthly subscription plan is not a practical option.

What Do Online Reviews Say About ZuPoo?

I believe that it’s essential to read online reviews of a product that you’re planning to add to your daily life. That’s because they provide valuable insights and real-life experiences from other users who have already tried the product.

I always follow this practice because it helps me determine if it’s a worthwhile investment of my time and money and if it aligns with my needs and preferences. I did the same with the ZuPoo supplement, and here’s what I found.

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Screenshot from

ZuPoo supplement worked for Thomas just as the company advertises. It took about 48 hours to remove waste material from their body. However, they didn’t experience any weight loss because the product doesn’t directly help with that.

Paul Antinoro
Screenshot from
Paul Antinoro
Screenshot from

While Paul didn’t experience anything too dramatic, he seems satisfied with the product. But as I’ve discussed already, the product is expensive, and the user also doesn’t seem happy about its price.

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Screenshot from

I totally agree with Julee because it’s true that one size doesn’t fit all. I hope she’ll find another product that helps her out.

How Much Does ZuPoo Cost?

A single jar of ZuPoo containing 30 capsules (that makes for a 15-day supply) costs $34.44 if you buy it from the official website. But if you plan to purchase this supplement from any other store, you might need to pay even more.

For example, it’s available for more than $40 on Amazon. This price tag makes ZuPoo Colon Cleanse an expensive product, especially for those who are on a tight budget.

ZuPoo vs. Alternatives

There are many other popular supplements available in the market that you can consider instead of ZuPoo. I’ve selected the best ones depending on their quality and effectiveness.

If you’re concerned about taking ZuPoo because of its potential side effects, you can consider the following options.

Comparison Winner: ColonBroom
Bye Bye Bloat
Goli Supergreens Gummies
Perfect Flush
Herbal Power Flush

Organic and natural ingredients

Vegan and fast-friendly


Boosts energy and metabolism



Promotes weight loss

Clears and cleans the digestive tract

May help manage blood sugar and lower cholesterol

Increases daily fiber intake

Water weight management

Gluten and dairy-free

Supports the gut

Increases daily fiber intake


Contains essential vitamins and minerals

Supports overall health


May help with weight loss

Laxative effect is mild

Promotes regularity

May support weight loss

Contains digestive enzymes

Promotes regularity


More expensive than some brands

May take time to adjust to the fiber intake, causing bloating

Short-term use

May cause unpleasant symptoms such as gas

Not vegan-friendly 

May cause adverse side effects

May take up to 6 weeks to see results

Not vegan-friendly

No taste

Contains wheat dextrin that may be unsuitable for gluten intolerances

Contains sugar

May cause adverse side effects

May cause adverse side effects

Receives some negative reviews with claims it doesn’t work for some people

Not suitable for everyday use


Who should use ZuPoo?

ZuPoo works best as a laxative and can be used as temporary relief for those who suffer from occasional constipation. It should not be used as a long-term supplement.

Where can I buy ZuPoo?

You can buy ZuPoo Colon Cleanse from the official UMZU website and Amazon.

Is UMZU ZuPoo vegan?

No, ZuPoo is not vegan. While the contents are vegan-friendly, the capsule is made from bovine gelatin.

How I Tested

To evaluate a product that I’m testing properly, I use a systematic approach. I consider its overall quality, effectiveness, price, and brand reputation to figure out if it’s worth the time and money.

Read on to learn more about these factors to determine if ZuPoo is the right choice for you.

Quality 9/10

I must say that the overall quality of the ingredients, packaging, and product presentation is up to the mark. It’s worth noting that I’m only talking about the quality, not their effects or anything else.

Effectiveness 7/10

For many people, the ZuPoo supplement works effectively to remove waste from the body. However, there are users who didn’t experience any difference after taking it.

Additionally, the ingredients it contains can also affect your health negatively, which is something no one wants to experience.

Price 6/10

As I’ve already mentioned a couple of times, ZuPoo is a very expensive product. It’s costlier than most supplements of the same category that you can buy from the market. In my opinion, the price tag of this supplement can be a deal breaker for many people.

Brand reputation 8/10

UMZU is known for offering products made from natural ingredients, which is a positive aspect. However, some of the ingredients used in ZuPoo Conlon Cleanse can affect your health negatively.

Additionally, the company is also relatively young and still needs time to establish itself firmly in the market.

ZuPoo: The Final Verdict

ZuPoo Colon Cleanse is a decent supplement that you can use to clean your gut and get rid of constipation. It comes with laxative properties that can relieve a blocked colon within 48 hours.

However, that’s about all it does. Plus, many of the ingredients are questionable, making it an unsuitable solution for regular use.

If you have digestive issues and are looking for a supplement that you can take regularly, you can consider opting for fiber or probiotic supplements.

Regardless of the option you choose, make sure that you talk to your healthcare provider before you start taking it.

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Written by Edibel Quintero, RD
Fact checked by Rosmy Barrios, MD
Last update: September 21, 2023
14 min read 1967 Views 0 Reviews
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