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7 Best Appetite Suppressants to Try This Year
Weight Loss

7 Best Appetite Suppressants to Try This Year

HR_author_photo_Edibel
Written by Edibel Quintero, RD | Medically reviewed by Medically reviewed by Rosmy Barrios, MD check
Published on November 7, 2022
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10 min

If you are trying to lose weight, there are many ways you can do it. One of the most effective ways is using appetite suppressants. In this article, we’ll show you which supplements are the most effective for controlling cravings and have the most benefits so you can decide on the one that meets your goals.

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Many people, especially those on a weight loss journey, struggle to control their unhealthy snacking and uncontrollable hunger. 

With all those mouthwatering foods in your favorite eatery and the abundance of snack choices, it can seem impossible to fight your food cravings and weight gain. 

Luckily, there are many appetite suppressant supplements available that might help.

The best appetite suppressant supplements to help you lose weight have ingredients that may help you stay on track with your diet by reducing hunger and food cravings, boosting your metabolism, burning fat, and increasing your energy levels.

However, given the wide variety of OTC appetite suppressants, selecting effective ones might be challenging.

We have reviewed the best appetite suppressants to determine the most effective ones. We evaluated each weight loss supplement, considering different factors that include efficacy, ingredients, quality, pricing, and reviews. 

Here are the best appetite suppressants you can choose from.

The Best Appetite Suppressant of 2022: 7 Recommendations From a Nutritionist

You don’t want to take an appetite suppressant that will make you feel crazy or uncomfortable. It’s important to choose a supplement that uses natural ingredients and has been tested by experts. Here are the 7 best appetite suppressants:

#1 DoFasting Box – Best overall

Dofasting Supplements
Fresh Line of Weight Loss Supplements
  • Suppresses appetite
  • Reduces cravings
  • Encourages fat loss
Our rating:
4.7
Check Current Pricing

DoFasting Box is our best choice – the best overall appetite suppressant to control hunger and help you lose weight. 

The DoFasting Box is a weight loss box designed to simplify fasting. These supplements are vegan, gluten-free, and created in the US. The company claims these products are made with organic and all-natural ingredients to support the intermittent fasting lifestyle.

The Essential Fiber Complex in this box reduces hunger pangs during intermittent fasting and offers other additional benefits, including lowering blood pressure, triglycerides, and cholesterol levels, to protect against heart disease.

Additionally, fiber can help soothe diarrhea, make you poop, and regulates blood sugar levels in people with or at risk for diabetes.

DoFasting Box contains powerful, natural appetite suppressant ingredients, cellulose and glucomannan. These are non-soluble sources of fiber, meaning the body does not absorb them. They absorb water in your stomach, making you feel full. 

Cellulose supports the digestive system and helps detoxify the body by cleaning the colon. Given that its colon-cleansing effects promote regular bowel movements, it’s effective in relieving constipation. 

Glucomannan is low in calories, so taking this supplement during your fasting window won’t break your fast.

The company provides free shipping within 4–7 days and a 30-day money-back guarantee.

Besides DoFasting supplements, the company also offers the DoFasting app, which gives personalized intermittent fasting plans, reminders, recipe ideas, tips, and exercise routines to help you get the most out of your intermittent fasting diet.

You also have access to a comprehensive FAQ section and an educational blog. These elements work together to give you a ton of knowledge and make it possible for you to go through prolonged fasting without any difficulty.

Pros
  • 30-day money-back guarantee
  • Free worldwide shipping
  • Very low calorie count
  • Great natural taste
Cons
  • Pricey

#2 Klinio Box – Best for those with diabetes

Klinio Supplements
Enhance your weight loss results
  • Accelerates fat burn & fat loss
  • Lower bad cholesterol
  • Crush your hunger pangs
  • Boosts your metabolism
  • Enhances natural calorie burn
  • Boosts energy levels & performance
Our rating:
4.4
Learn More

The Klinio Box provides a different approach for persons with type 2 diabetes, prediabetes, or obesity to control their blood sugar while losing weight without adhering to a rigorous diet or exercise regimen.

This box provides the body with the nutrition it needs to produce more insulin. Along with regulating other important elements like blood pressure, cholesterol, and blood sugar levels, it also increases metabolism, curbs hunger, and suppresses the desire for sweet cravings.

This supplement contains ingredients like cellulose and glucomannan, which have been shown to help people with diabetes lose weight and control their blood sugar levels.

The primary ingredient of Klinio supplements, glucomannan, is a source of soluble fiber that forms a protective film on the gut wall to extend the time food stays in your stomach, enhancing feelings of fullness and reducing appetite. This helps digestion and prevents sugar and cholesterol from being absorbed immediately.

Cellulose promotes regular bowel movements, speeds up the transit of food through your digestive system, and reduces constipation.

Pros
  • Gluten-free
  • Low calorie count
  • Vegan-friendly
  • Free US shipping
Cons
  • Price

#3 Keto Cycle FUEL – Best for keto dieters

KetoCycle Fuel
  • Easy transition into ketosis
  • Increased metabolism and fat burning
  • Sustained and consistent weight loss
Our rating:
4.7
Check Current Pricing

Keto Cycle FUEL is one of the top-selling ketogenic diet supplements on the market. This supplement offers many benefits to streamline and simplify your keto lifestyle while giving you the feeling of satiety.

Keto Cycle contains whey protein, MCT oil, collagen peptides, and electrolytes. Taking this supplement can help you burn body fat by using it as energy and increase blood ketone levels.

You may experience fatigue on the keto diet, especially in the first few weeks, as your body gets used to eating fewer carbohydrates. As a result, using a keto supplement like Keto Cycle can help boost the energy you need to stick to your diet and not overeat.

This keto combination has exogenous ketones, which increase energy and boost performance. The ketones in Keto Cycle also alleviate keto flu symptoms, like brain fog, and can help you stick to your diet plan by making it simpler to limit calories and carbs.

Keto Cycle FUEL contains electrolytes like magnesium and sodium, which are important for keeping your body balanced and hydrated while following a ketogenic diet. Electrolyte imbalance is the main leading factor in keto flu.

This appetite suppressant comes with a 14-day money-back guarantee, allowing you to try this keto diet supplement without a monetary commitment. If you feel that Keto Cycle doesn’t meet your needs, you can return your unused bottles and get a full refund.

You can also save money by buying several Keto Cycle FUEL bottles in a single order. Buying two bottles gives you one free, while buying three bottles gives you two free ones. Overall, Keto Cycle is a trustworthy keto diet supplement that has all the ingredients you need to follow the keto diet.

Pros
  • Gluten-free
  • Low calorie count
  • Made in the USA
  • Great flavors
Cons
  • Not vegan-friendly
  • Will break your fast

#4 PhenQ – Best with Capsimax powder

PhenQ
  • Increases fat burning
  • Blocks fat production
  • Increases energy
  • Balances mood
  • Scientifically proven formula
Our rating:
4.3
Learn More

PhenQ is a weight loss supplement with ingredients that have been shown to suppress appetite and boost metabolism, making it an effective appetite suppressant. 

PhenQ weight loss supplement helps you lose weight in multiple ways, including suppressing appetite, burning fat, boosting energy, stopping fat production, and improving your mood.

The ingredients in this product include caffeine, nopal cactus fiber, Capsimax powder, L-carnitine fumarate, and chromium picolinate. They may help you burn more calories throughout the day through a more powerful thermogenic effect.

Capsimax powder has a blend of other ingredients, like caffeine, capsicum, and vitamin B3, that can help you increase your body’s temperature and burn more calories than usual. Chromium picolinate is a naturally occurring mineral in whole grains, fruits, and meat. Its main purpose is to efficiently regulate blood sugar levels by reducing sugar and carb cravings.

Caffeine, the most well-known ingredient, may rejuvenate the body and give quick energy. Additionally, caffeine stimulates thermogenesis and fat burning and can help suppress appetite.

The company offers a 60-day money-back guarantee, allowing you to return the supplement and receive a full refund if unsatisfied.

Pros
  • 60-day money-back guarantee
  • Free shipping
  • All-natural ingredients
  • No need for prescription
Cons
  • Can affect sleep quality
  • Not suitable for pregnant women and children
  • Can only be purchased from the official website

#5 Leanbean – Best for steady energy support

Leanbean
  • Boosts metabolism
  • Helps burn fat faster
  • Improves mood
Our rating:
3.6
Learn More

Leanbean is one of the best known appetite suppressants for women. The manufacturer of this supplement knows that men and women lose weight in different ways. According to recent research, women typically experience stronger hunger pangs than men and have more difficulty overcoming these cravings.

This natural fat burner helps you lose weight by increasing energy levels, reducing hunger, accelerating fat burning, enhancing mood, and curbing cravings.

Leanbean supplement helps you get the physique you want by flattening your belly and firming up your glutes. It also encourages you to become more energetic and active. 

Its primary ingredients include glucomannan, choline, vitamin B6, vitamin B12, chromium picolinate, turmeric, Garcinia Cambogia, green coffee beans, and acai berry.

Glucomannan is the main ingredient and an effective appetite suppressant in the formula. It’s a water-soluble dietary fiber obtained from the elephant yam tuber or root known as konjac. Glucomannan forms a viscous gel in the stomach, making you feel fuller for longer and reducing your urge to eat.

When consumed frequently, glucomannan has also been found to help reduce total body weight and control blood sugar.

Leanbean daily dose is 6 pills. You will consume 2 tablets with every meal. The tablets don’t include stimulants, so you can take them in the afternoon without worrying about how they’ll affect your sleep.

Pros
  • 90-day money-back guarantee
  • No shipping cost
  • Thousands of positive reviews
Cons
  • Money-back guarantee is limited to bundles
  • Only targeted at women
  • Very high daily dose (6 pills)

#6 Phen24 – Best for balancing cortisol levels

Phen24
  • Promotes better sleep
  • Reduces stress
  • Helps burn fat
  • Boosts metabolism
Our rating:
4.2
Learn More

Phen24 is another diet pill that works by boosting your metabolism. It comes with two appetite-suppressing supplements that operate around the clock to increase your metabolism and ensure you lose weight even when you’re asleep.

Phen24 is designed to increase energy levels and limit your food cravings. Its formula contains potent thermogenic and effective stimulants, including cayenne powder, caffeine, manganese, copper, zinc, and l-phenylalanine.

A high cortisol level is linked to increased fat storage, a slowed metabolism, irregular sleeping habits, mood changes, and irritability. Phen24 balances your body’s cortisol levels and reverses its effects.

The company says that Phen24 is not a magic pill. You need to change your lifestyle by including healthy doses of exercise since Phen24 needs the help of increased activity to enhance your metabolism day and night. 

However, there are many similarities between PhenQ and Phen24, so you can try them both and see which product works best for you.

Pros
  • 60-day money-back guarantee
  • Offers free shipping
  • Third-party-tasted
  • Uses natural ingredients only
Cons
  • Daytime formula has stimulants
  • Not good for those on antidepressants

#7 Instant Knockout – Best for boosting metabolism

Instant Knockout
  • Boosts energy and metabolism
  • Some ingredients help to burn fat
  • Reduces your calorie intake
Our rating:
3.9
Learn More

Instant Knockout is one of the best-known appetite suppressants that help men control hunger and lose body fat. It contains organic stimulants that boost metabolism and energy to help you power through your day.

Athletes who want to lose weight without losing muscle should consider using Instant Knockout. Although these diet pills were created with MMA athletes in mind, they benefit any athlete looking to drop some pounds and get into shape.

The powerful capsules contain a few well-known ingredients, like green tea extract, cayenne pepper seeds, green coffee bean extract, and glucomannan powder, alongside vital nutrients and vitamins like vitamin B12, zinc, and GTF chromium.

Because of its well-known ability to reduce hunger, glucomannan is a crucial ingredient in this product’s success. It makes it easier to resist the urge to snack between meals and keeps you full throughout the day. Caffeine is an essential stimulant that helps speed up your metabolism and fat-burning after exercise.

The company uses GMP-certified and FDA-registered facilities to ensure high-quality products made only using ingredients that come from natural sources.

Pros
  • Vegan-friendly
  • 30-day money-back guarantee
  • Offers a subscription plan
Cons
  • Large and difficult-to-swallow capsules
  • High in caffeine
  • Can only be bought from the official website
  • May cause bloating and upset the stomach

Comparison of the Best Appetite Suppressants

DoFasting Box
Keto Cycle FUEL
Klinio Box
PhenQ
Phen24
Instant Knockout
Leanbean
4.7
4.7
4.4
4.3
4.2
3.9
3.6

30 day money-back guarantee

Free worldwide shipping

Very low calorie count

Great natural taste

Free worldwide shipping

14-day money-back guarantee

No added sugar

Contains electrolytes

Gluten-free

Low calorie count

Vegan-friendly

Free US shipping

60-day money-back guarantee

Free shipping

All-natural ingredients

No need for prescription

The brand is reputable, with many years of experience

Money-saving

60-day money-back guarantee

Offers free shipping

Third-party-tasted

Uses natural ingredients only

Vegan-friendly

30-day money-back guarantee

Offers a subscription plan

90-day money-back guarantee

No shipping cost

Thousands of positive reviews 

A bit expensive

Not vegan-friendly

Will break your fast 

Higher price point

Can affect sleep quality

Not suitable for pregnant women and children

Can only be purchased from the official website

Daytime formula has stimulants

Not good for those on antidepressants 

Cannot be consumed by children

Large and difficult-to-swallow capsules

High in caffeine

Can only be bought from the official website

May cause bloating and upset the stomach

Money-back guarantee is limited to bundles only

Brand
DoFasting Box
Keto Cycle FUEL
Klinio Box
PhenQ
Phen24
Instant Knockout
Leanbean
Rating
4.7
4.7
4.4
4.3
4.2
3.9
3.6
Pros

30 day money-back guarantee

Free worldwide shipping

Very low calorie count

Great natural taste

Free worldwide shipping

14-day money-back guarantee

No added sugar

Contains electrolytes

Gluten-free

Low calorie count

Vegan-friendly

Free US shipping

60-day money-back guarantee

Free shipping

All-natural ingredients

No need for prescription

The brand is reputable, with many years of experience

Money-saving

60-day money-back guarantee

Offers free shipping

Third-party-tasted

Uses natural ingredients only

Vegan-friendly

30-day money-back guarantee

Offers a subscription plan

90-day money-back guarantee

No shipping cost

Thousands of positive reviews 

Cons

A bit expensive

Not vegan-friendly

Will break your fast 

Higher price point

Can affect sleep quality

Not suitable for pregnant women and children

Can only be purchased from the official website

Daytime formula has stimulants

Not good for those on antidepressants 

Cannot be consumed by children

Large and difficult-to-swallow capsules

High in caffeine

Can only be bought from the official website

May cause bloating and upset the stomach

Money-back guarantee is limited to bundles only

How We Tested

Here is a thorough breakdown of all the criteria we used to choose our best appetite suppressants.

Quality 

We ensure the company is keen on the safety and quality of a product. The DoFasting appetite suppressant has been tested for quality and safety in third-party labs, so it is safe to use.

Effectiveness 

We make sure that the suppliers of these appetite suppressants provide 100% legitimacy and efficacy for every product in their line-up so that the clients can realize their goals in no time.

We have specifically conducted our research on DoFasting Box, Klinio Box, and the Keto Cycle FUEL supplements and confirm that each ingredient used is proven to promote weight loss through scientific studies.

Price 

The pricing range is another factor we consider. It’s not always true that the most expensive is the best. You are mistaken if you believe purchasing an expensive bottle of appetite suppressants will make them more effective than cheaper ones. As a result, our collection includes products with a range of prices but with high-quality standards.

Brand reputation

The brand should be reputable and with many years of experience. We ensure the brand we choose has experienced nutritionists, fitness experts, and medical consultants in charge of designing the product. The brand should also be prepared to assist the clients with each stage of accomplishing their goals.

A Word From Our Nutritionist

Appetite suppressants can help you control your hunger and start losing weight. Your healthcare professional can help you identify the ideal weight-loss pill or treatment strategy for your specific needs.

Certain lifestyle changes are essential to continue losing weight successfully. Remember that when you stop using appetite suppressants, their action stops. Therefore, it’s crucial to maintain a healthy diet and increase your physical activity.

Appetite-suppressing supplements can interact with medications such as anti-anxiety drugs or antidepressants. Additionally, they can make several medical conditions worse. If you have liver disease, hyperthyroidism, glaucoma, or heart disease, you should avoid taking appetite suppressants. Women who are pregnant or nursing should not take these supplements.

FAQs 

How do appetite suppressants work?

Appetite suppressants work by affecting the brain’s desire to eat. Diet pills might help you feel fuller more quickly with less food by controlling hunger. As a result, you eat fewer calories and shed some pounds.

Are appetite suppressants safe to use?

Yes, but only those natural appetite suppressants made with natural ingredients. The supplements listed above are risk-free and don’t have any artificial components that could harm your body. Any natural appetite suppressant should be researched and backed by science to ensure its efficacy.

What are the drawbacks of appetite suppressants?

As with any medication, appetite suppressants can occasionally have unwanted side effects, including nervousness, dizziness, insomnia, and digestive issues such as constipation, nausea, stomach pain, and diarrhea.

Conclusion

In our well-researched review, we have laid down the 7 best appetite suppressant supplements, along with their primary benefits. If you’re looking for the best appetite suppressant supplements to help you lose weight, we highly recommend using our overall best, the DoFasting supplement. 

Avoid appetite suppressants if you have medical conditions such as hyperthyroidism, liver disease, or glaucoma. Don’t take these supplements if you’re pregnant or breastfeeding.

Additionally, you must discuss your plan with your doctor. Choose natural appetite suppressant supplements over artificial ingredients. Any natural product you select will function best with a balanced diet and regular exercise.

HR_author_photo_Edibel
Written by
Edibel Quintero is a medical doctor who graduated in 2013 from the University of Zulia and has been working in her profession since then. She specializes in obesity and nutrition, physical rehabilitation, sports massage and post-operative rehabilitation. Edibel’s goal is to help people live healthier lives by educating them about food, exercise, mental wellness and other lifestyle choices that can improve their quality of life.
Medically reviewed by Rosmy Barrios, MD
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