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6 Best Probiotics for SIBO: Improve Your Overall Gastrointestinal Health
Gut Health

6 Best Probiotics for SIBO: Improve Your Overall Gastrointestinal Health

HR_author_photo_Edibel
Written by Edibel Quintero, RD | Fact checked by Fact checked by Rosmy Barrios, MD check
Last update: March 29, 2023
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6 min

Are you looking for something to treat small intestinal bacterial overgrowth? Probiotics might be able to help, but which one should you try? This article details the most effective probiotics to aid treatment and help rebalance the microorganisms in your gut.

Best probiotics for SIBO
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Small intestinal bacterial overgrowth, or SIBO, is a condition that occurs when there are more bacteria in the small intestine than normal. Usually, protective processes like gastric acid secretion and intestinal motility prevent excess bacterial growth. When these processes fail, bacteria can manifest.

Too much bacteria in the small intestine causes exhaustive digestive symptoms, such as gas, bloating, diarrhea, and abdominal pain. Left unchecked, it can trigger more severe health complications, including malnutrition and dehydration.

The condition is curable, although it may recur. Treatment requires identifying the underlying problem and may include antibiotic therapy and nutritional support. Probiotics might help your gut bacteria return to normal, but you must always follow your doctor’s advice.

In this article, we bring you the best probiotics to treat SIBO.

Comparing Probiotics for SIBO

Bioma
Align
Biotics 8
Microbiome Plus
Ritual Synbiotic+
HUM Gut Instinct
4.5
3.9
4.1
4
3.7
3.6

Improves digestion

Reduces gut discomfort

Reduces inflammation

Alleviates stomach pain, gas, and bloating

Prevents constipation and diarrhea

Single capsule

Well-known bacterium

Gluten-free and soy-free

Single capsule

Money-back guarantee

Improves digestion

Fortifies the immune system

Boosts testosterone levels

Increases energy levels

Supports mental well-being

Free from gluten and soy

Boosts the immune and digestive systems

Increases energy levels

Improves mental well-being

May support weight loss

Allergen-free

Relieves bloating, gas, and diarrhea

Supports gut barrier function

Boosts immune system

Vegan-friendly

Gluten-free and major allergen-free

No need to refrigerate

Regulates digestion

Boosts immune function

Promotes healthy skin

Vegan-friendly

No artificial ingredients

Expensive

Expensive

Contains milk

For men only

Results may vary

Requires 2 daily doses

Some customers found no results

Expensive

May cause discomfort at first

Proprietary blend

May cause temporary side effects

Brand
Bioma
Align
Biotics 8
Microbiome Plus
Ritual Synbiotic+
HUM Gut Instinct
Overall Rating
4.5
3.9
4.1
4
3.7
3.6
Pros

Improves digestion

Reduces gut discomfort

Reduces inflammation

Alleviates stomach pain, gas, and bloating

Prevents constipation and diarrhea

Single capsule

Well-known bacterium

Gluten-free and soy-free

Single capsule

Money-back guarantee

Improves digestion

Fortifies the immune system

Boosts testosterone levels

Increases energy levels

Supports mental well-being

Free from gluten and soy

Boosts the immune and digestive systems

Increases energy levels

Improves mental well-being

May support weight loss

Allergen-free

Relieves bloating, gas, and diarrhea

Supports gut barrier function

Boosts immune system

Vegan-friendly

Gluten-free and major allergen-free

No need to refrigerate

Regulates digestion

Boosts immune function

Promotes healthy skin

Vegan-friendly

No artificial ingredients

Cons

Expensive

Expensive

Contains milk

For men only

Results may vary

Requires 2 daily doses

Some customers found no results

Expensive

May cause discomfort at first

Proprietary blend

May cause temporary side effects

Review

6 Best Probiotics for SIBO treatment

Antibiotics remain the initial treatment option to eliminate the overgrowth of bacteria in the small intestine. Taking probiotics can be effective in treating SIBO. More research is necessary, but it is thought that the beneficial bacteria might help to restore healthy microbiota.

Generally, probiotics are among the top gut health hacks. That’s why our team has chosen 6 probiotic supplements that may help with SIBO symptoms and promote better gastrointestinal health. Keep reading as we uncover each product’s key features, advantages, and drawbacks.

#1 Bioma – Best overall

Bioma
  • Rebalances bacteria in the gut microbiome
  • Supports weight management and digestive health
Our rating:
4.5
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Bioma is a probiotic supplement designed for gut and weight management. It contains xylooligosaccharide (XOS), a prebiotic that improves intestinal microbial structure, reduces inflammation, and modifies gut bacterial composition.

Tributyrin has the ability to enhance gut health by boosting the immune system and protecting it from oxidative stress. A stronger immune function fights off unwelcomed bacteria, preventing them from growing and resulting in small intestine bacterial overgrowth.

SIBO risk increases in those with a weakened immune system, so building strong immune responses is crucial in combating and preventing the condition.

Bioma has many qualities that may reduce symptoms in SIBO patients. After fixing the imbalance of harmful bacteria, users can expect relief from stomach pain, diarrhea, and discomfort after eating. It might be one of the best probiotics for bloating – another SIBO symptom.

Another bonus is Bioma’s targeted-release capsules. These capsules are made to survive stomach acid and the journey to your intestines. You don’t have to worry about your body accidentally destroying the probiotics before they do their job.

Pros
  • Improves digestion
  • Reduces discomfort in the gut
  • Reduces gut inflammation
  • Alleviates stomach pain, gas, and bloating
  • Alleviates constipation and diarrhea
  • Cleanses the body
  • Self-activating ingredients
  • Convenient daily capsule
Cons
  • Fairly expensive
  • Results might differ from person to person

#2 Align – Best for occasional symptoms

Align
  • Helps to alleviate occasional abdominal pain, gas, and bloating
  • Fortifies the digestive system with friendly bacteria
Our rating:
3.9
Learn More

Align is a digestive support supplement designed to help people with occasional problems like gas and bloating. It can relieve abdominal pain and promotes an overall healthy digestive system by providing your body with adequate amounts of friendly bacteria.

It contains the well-known probiotic strain Bifidobacterium longum 35624. Align claims to be the only supplement containing this strain, which can change the structure of the gut microbiota and is recognized for its role in certain digestive disorders.

The most notable health benefit of Bifidobacterium longum 35624 is its ability to reduce disease severity in people with irritable bowel syndrome (IBS). As many SIBO and IBS symptoms are the same, taking this probiotic strain might benefit people with SIBO.

Moreover, many people have both conditions. Treating the SIBO symptoms can simultaneously help alleviate IBS.

Pros
  • Contains a well-studied bacterium
  • May be effective for IBS patients
  • Gluten-free and soy-free
  • Convenient single capsule
  • Money-back guarantee
Cons
  • Contains milk
  • More expensive than many probiotics

#3 Biotics 8 – Best for men

Biotics 8
  • Helps regulate the gut microbiome
  • Purposefully made to support men’s gastrointestinal health
Our rating:
4.1
Learn More

Biotics 8 is a probiotic product specifically made for men. It contains probiotics and prebiotics to help your gut microbiome thrive. Digital enzymes break down the fats, proteins, and sugars in foods without causing discomfort, such as gas and other unpleasant symptoms.

The supplement also claims to support proper bowel movements, increased energy levels, and a more robust immune system. The formula contains 10 active probiotic strains, including Lactobacillus plantarum, which may have qualities that benefit both SIBO and IBS patients.

It also contains chicory root prebiotic fiber and additional vitamins. More fiber in your diet can help regulate bowel movements and reduce diarrhea.

Pros
  • Improves digestion
  • Fortifies the immune system
  • Boosts testosterone levels
  • Increases muscle growth
  • Enhances energy levels
  • Supports mental wellness
  • Improves focus
  • Gluten-free and soy-free
Cons
  • Marketed for men only
  • Not everyone will experience the same results

#4 Microbiome Plus – Best allergen-free

Microbiome Plus
  • Contributes to better immunity and digestive health
  • Supports cardio-metabolic issues
Our rating:
4
Learn More

Microbiome Plus is an award-winning range of probiotic products that work to improve gastrointestinal health. The ingredients include Lactobacillus reuteri – possibly one of the best SIBO probiotics because it has antimicrobial compounds to prevent the overgrowth of pathogenic bacteria.

Lactobacillus reuteri is helpful for modulating the gut flora, preventing bowel movement difficulty, and attenuating the symptoms of various digestive disorders, including irritable bowel syndrome, inflammatory bowel disease (IBD), and chronic constipation.

Pros
  • Contains Lactobacillus reuteri
  • Boosts immune and digestive health
  • Increases energy levels
  • Improves mental well-being
  • Contributes to weight loss
  • Allergen-free
Cons
  • Requires two daily doses
  • Some customers report no noticeable results

#5 Ritual Synbiotic+ – Best gluten-free

Ritual Synbiotic+
  • Promotes a healthy gut
  • Reduces uncomfortable digestive symptoms
Our rating:
3.7
Learn More

You can support a normal balance of good and bad bacteria in your gut with Ritual Synbiotic. The formula is designed to target the pathogenic strains of bacteria and boost the growth of the healthy kind to help you feel better overall.

This supplement contains 11 billion colony-forming units (CFUs) with a probiotic blend that includes two clinically-studied strains: Lactobacillus rhamnosus and Bifidobacterium animalis ssp. lactis.

Lactobacillus rhamnosus is the largest genus of the lactic acid bacteria group. Studies show it can be effective in alleviating SIBO symptoms. It may also improve your intestinal barrier function to prevent a leaky gut.

Bifidobacterium animalis ssp. lactis has various positive effects on the gut. Research suggests it can relieve gut dysmotility, increase stool frequency, and improve stool consistency.

Pros
  • Relieves bloating, gas, and diarrhea
  • Supports gut barrier function
  • Contributes to good immune health
  • Vegan-friendly
  • Gluten-free and major allergen-free
  • Third-party tested
  • No refrigeration needed
  • Single daily capsule
Cons
  • Expensive
  • May cause discomfort in the beginning

#6 HUM Gut Instinct – Best vegan formula

HUM Gut Instinct
  • Restores balance to the gut microbiota
  • Decreases bloating and other digestive problems
Our rating:
3.6
Learn More

Gut Instinct from HUM Nutrition is a potent probiotic for a well-balanced gut. It boosts immunity, increases friendly bacteria, and generally nurtures the gut. It contains 10 different strains that provide your body with a bacterial boost, with Lactobacillus and Bifidobacterium species to support healthy gut diversity.

People with SIBO often feel pain and discomfort after eating a meal. Gut Instinct promotes better digestion to help prevent those nasty symptoms like feeling bloated, full, and gassy. Lactobacillus acidophilus helps your body break down food and absorb important nutrients. 

You can take one capsule daily and see how it makes your body feel after consuming food. Another good thing about this supplement is that it contains clean, vegan-friendly ingredients. It is free from many common allergens, including wheat, soy, gluten, milk, egg, and fish.

Pros
  • Regulates digestion
  • Boosts immune function
  • Improves skin health
  • Clean ingredients
  • Vegan-friendly
  • Single daily capsule
  • Third-party validated
  • No artificial flavors, sweeteners, or preservatives
Cons
  • The proprietary blend makes the exact ingredients unclear
  • May cause temporary digestive upset

How We Tested These Probiotics

We explored some critical factors in picking the products for this review. Aside from a general overview of each product, we zoned in on the quality, effectiveness, price, and brand reputation. These essential aspects help to ensure a product is a good choice for the consumer.

Let’s look at this in more detail.

Quality

The quality of a probiotic product is of utmost importance. High-quality products contain probiotic strains that are well-researched and known to deliver health benefits. They should also have a sufficient number of colony-forming units to produce noticeable effects.

Effectiveness

Assessing the effectiveness is a bit more tricky because not everybody will respond in the same way to a particular probiotic strain. However, those with well-known probiotic strains are likely to work best. The dose is, again, critical, as low doses can make a supplement ineffective.

Price

Pricing is key if you want to take probiotics daily. The probiotics in this review range in price. This gives you options when looking for the best probiotics for SIBO to suit your budget. A higher price does not necessarily make one probiotic better than another. You should review the price according to the brand’s quality, potential efficacy, and reputation.

Brand reputation

The probiotics listed here are from reputable brands, and brands with good reputations are more likely to deliver results. You can find more information about each company by visiting their official websites. This can help you understand their ethos and their goals for consumers.

A Word From a Doctor

Small intestinal bacterial overgrowth is the presence of excess bacteria in the small intestine. SIBO develops when the passage of food and waste through the digestive tract slows or becomes stagnant. This enables an environment for bacteria to grow excessively.

It might occur from certain health conditions that slow the motility of food and waste products, such as Crohn’s disease, celiac disease, and diabetes. Other causes include surgery complications (primarily stomach surgery) or structural issues with the small intestine.

Your doctor might suggest treatments to improve nutritional deficiencies, such as dietary supplements. Dietary changes can help reduce the bacterial populations living in the gastrointestinal system. Fermented foods tend to work well for people with digestive woes.

Probiotics can help to alleviate SIBO symptoms by modulating the gut microbiota to restore the balance of good and bad bacteria. Furthermore, taking probiotics may enhance the effectiveness of antibiotics and reduce symptoms of antibiotic-associated diarrhea.

Conclusion

As you can see above, there are plenty of probiotic supplements to help restore your gut. Bioma might be the best probiotic for fixing bacteria imbalance and supporting a happy and healthy gut. It contains probiotic strains that can improve the structural elements of your gut.

Still, you must talk to your doctor about the best cures and probiotics for SIBO. They can help to identify the best probiotic strain to treat the condition. SIBO is serious and requires appropriate action before symptoms worsen.

HR_author_photo_Edibel
Written by
Edibel Quintero is a medical doctor who graduated in 2013 from the University of Zulia and has been working in her profession since then. She specializes in obesity and nutrition, physical rehabilitation, sports massage and post-operative rehabilitation. Edibel’s goal is to help people live healthier lives by educating them about food, exercise, mental wellness and other lifestyle choices that can improve their quality of life.
Fact checked by Rosmy Barrios, MD
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