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Home arrow Health arrow Gut Health arrow Best Probiotics for Leaky Gut: 7 Options to Restore Your Gut Balance

Best Probiotics for Leaky Gut: 7 Options to Restore Your Gut Balance

HR_author_photo_Edibel
Written by Edibel Quintero, RD
HR_author_photo_Rosmy
Fact checked by Rosmy Barrios, MD
Last update: September 6, 2023
7 min read 1120 Views 0 Reviews
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Leaky gut syndrome can debilitate people in their everyday lives. Symptoms like cramps and bloating are especially challenging, but are there ways to feel relief? Discover the best probiotic supplements for leaky gut.

best probiotics for leaky gut

How do we vet brands and products? Learn more.

Probiotics contain beneficial bacteria that could support your gut.

Some people take dietary supplements to treat their unique symptoms, but do they work for leaky gut syndrome, as well? This is something you might question when dealing with inflammation, cramps, bloating, and painful indigestion. 

Any form of probiotic that contains active cultured strains typically supports gut health and treats a wide variety of gut-related problems. It’s important to choose the right supplement if you want to reduce leaky gut and suffer fewer side effects. 

Keep reading to discover the best probiotics for leaky gut. 

Top 3 Probiotics for Leaky Gut

#1 Best overall star
bioma logo
4.5
stars
  • Restores balance in the gut
  • Helps with weight management
  • Improves digestion
  • Reduces hunger and cravings
Visit Klaire Labs
Visit Bioma
#2
Klaire Labs logo
4.3
stars
  • Helps with back pain and gas
  • Replenishes the gut flora
  • Supports the growth of a healthy microbiome
Visit Klaire Labs
Visit Klaire Labs
#3
Probulin logo
4.2
stars
  • Reduces bloating
  • Aids digestion
  • Regulates the growth of good bacteria
Visit Klaire Labs
Visit Probulin

7 Best Probiotics for Leaky Gut: The Ultimate Guide

There are many probiotics that could help soothe a leaky gut from reducing bloating and improving nutrient absorption to relieving other pain and boosting overall well-being. It’s all about the ingredients and bacteria strains that work to replenish your intestinal lining.

Here are 7 probiotics that can support those with leaky gut syndrome: 

#1 Bioma – Best overall

bioma logo
Our rating:
4.5
stars
  • Rebalances bacteria in the gut microbiome
  • Supports weight management and digestive health
  • Relieves diarrhea and constipation
  • Free shipping
  • 14-day money-back guarantee
  • Improves digestion
Click Here to Start Bioma Quiz

Bioma is a probiotic supplement that replenishes the microorganisms in your gut. This can help reduce bloating, gas, cramps, and serious constipation

Some of the main ingredients comprise xylooligosaccharide (XOS), tributyrin, thermogenic strains, and delayed-release materials. A natural formula is best for strengthening the intestinal lining in those with leaky gut syndrome. 

Research suggests that XOS, a type of prebiotic, can reduce inflammation and strengthen structural components of your gut. You can safely ingest this ingredient to help your gut lining recover from damage. Also, XOS inhibits the growth of bad bacteria, which contributes to a leaky gut.

Moreover, tributyrin is a triglyceride that enhances probiotic bacteria. It keeps your gastrointestinal tract healthy while boosting normal bowel function. 

Pros
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    Reduces gut discomfort
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    Increases energy levels
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    Ensures better digestion
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    Reduces painful bloating
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    Prevents hunger cravings
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    Decreases inflammation
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    Maintains muscle mass
Cons
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    Possible minor side effects like gas
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    Results can differ from person to person
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    Requires consistent use

#2 Klaire Labs Ther-Biotic – Best for excess gas

Klaire Labs logo
Our rating:
4.3
stars
  • Can support your gastrointestinal tract
  • Each strain also helps to reduce flatulence
Learn More

Klaire Labs probiotics can treat IBS symptoms like back pain and gas while reducing leaky gut. This may help prevent harmful substances from penetrating your gut lining. 

The formula mainly comprises lactobacillus and bifidobacterium strains. One of these includes lactobacillus salivarius, which protects digestive enzymes from bacterial infections. It can also replenish your gut flora to reduce abdominal pain, constipation, bloating, and flatulence.

Bifidobacterium breve has a low CFU count, but it can still relieve stomach pain associated with leaky gut and inflammatory bowel diseases. This strain specifically lowers the risk of gastrointestinal infections in children and infants. 

An ingredient like streptococcus thermophilus also makes this supplement interesting. The probiotic bacteria produce lactic acid in the gut to reduce leaky gut. Lactic acid supports a healthy microbiome in those with leaky gut or IBS. 

Pros
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    Stops excess gas production
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    Might reduce fatigue and brain fog
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    Improves digestion
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    Regulates bowel movement
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    No artificial ingredients
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    Strengthens intestinal barrier integrity
Cons
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    Needs refrigeration
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    A lack of scientific evidence
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    Not suitable for those on a budget

#3 Probulin – Best for bloating 

Probulin logo
Our rating:
4.2
stars
  • Strengthens good bacteria in the gut microbiome
  • The active formula works to reduce leaky gut
Learn More

Probulin can help reduce bloating for those who have leaky gut syndrome. This is because it contains 20 billion colony-forming units and 15 strains with optimal potency. 

Supplements with a higher CFU count will strengthen beneficial bacteria. The more good bacteria you have, the more likely you can fight inflammation. 

Strains like lactobacillus bulgaricus can aid digestion by maintaining the balance between good and bad bacteria in your gut. A strong digestive system means you won’t get as much bloating or excess gas

Another ingredient, which is brown seaweed, plays a huge role in gut health. It helps to metabolize short-chain fatty acids and regulate the growth of good bacteria. This means you’ll have less intestinal gas and leaky gut symptoms. 

Pros
  • checkmark
    Reduces bloating
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    No refrigeration needed
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    Delayed-release capsules
  • checkmark
    Contains lactobacillus and bifidobacteria
  • checkmark
    Helps to prevent stomach cramps
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    Supports immune health
Cons
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    Might be expensive in the long term
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    Reports of poor packaging
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    Could trigger constipation

#4 Just Thrive Probiotic & Antioxidant – Best for constipation 

Just Thrive logo
Our rating:
4.0
stars
  • The formula fuels your gut with antioxidants
  • Supports immune, digestive, and overall body health
Learn More

Just Thrive is best suited to those who suffer from constipation and leaky gut syndrome. The unique formula produces antioxidants once your body absorbs the capsules. 

A study found that antioxidants in these types of probiotics relieve symptoms of inflammatory bowel disease and increase the good bacteria roaming your digestive tract. Because of the Just Thrive formulation, you are more likely to avoid constipation after eating certain foods. 

Some of the ingredients include bacillus indicus, bacillus subtilis, bacillus coagulans, and bacillus clausii. The creators of Just Thrive believe that the bacillus subtilis strain defends your gut against harmful pathogens. This is especially good for people who have leaky gut and need more good bacteria to protect their intestines. 

Also, the bacillus coagulans strain can reduce constipation and related problems like headaches, abdominal cramps, back pain, and infrequent bowel movement. 

Pros
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    Relieves constipation
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    Promotes healthy skin
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    Increases energy levels
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    Boosts nutrient absorption
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    Keto and vegan-friendly
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    Can prevent stomach ache
Cons
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    Some side effects like bloating and headaches
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    Has to be taken with food
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    Expensive shipping

#5 Align 24/7 Digestive Support – Best for digestion

ALIGN LOGO
Our rating:
3.9
stars
  • Boosts the digestive enzymes in your stomach
  • Prevents constipation after eating big meals
Learn More

Align 24/7 Digestive Support can boost digestion in those with leaky gut. This is because the active bacteria strengthen your gut lining while the body digests food. 

Bifidobacterium longum is the only strain found in this supplement. It depletes bad bacteria that disrupt digestion and cause stubborn constipation. Alongside that, this strain colonizes your gastrointestinal tract, which can help microorganisms repair the stomach wall from a leaky gut. 

Some other ingredients comprise microcrystalline cellulose, hypromellose, sodium caseinate, and magnesium stearate. A study found that microcrystalline can maintain a healthy gut flora while protecting the supplement as it travels through stomach acid. 

Align doesn’t have many strains, but it can still work when you take the probiotics in the morning with a high-fiber breakfast. 

Pros
  • checkmark
    Supports good digestion
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    Inexpensive supplement
  • checkmark
    Reduces bloating and gas
  • checkmark
    Boosts the immune system
  • checkmark
    Suitable for IBS symptoms
  • checkmark
    Can prevent constipation
Cons
  • checkmark
    Contains one strain
  • checkmark
    Reports of people getting stomach cramps
  • checkmark
    Can cause nausea

#6 Seed – Best for immunity 

Seed Logo
Our rating:
3.8
stars
  • Strengthens your digestive and immune system
  • Helps the body fight off inflammation
Learn More

Seed has been engineered to withstand stomach acid and reach your gut microbiome. This is due to the natural capsules that are made with chlorophyllin and fermented gellan gum. 

A study found that chlorophyllin reduces intestinal inflammation. People with leaky gut syndrome can experience fewer cases of bloating, cramps, and gas. The same goes for gellan gum and its role in balancing gut flora

Some other ingredients comprise bifidobacterium longum, lactobacillus crispatus, and bifidobacterium lactis. These are just a few out of the 20+ strains listed on the Seed website. 

Bifidobacterium longum can help the immune system repair your gut lining. In turn, those with stronger intestines will have reduced leaky gut in the long term. Alongside this ingredient, lactobacillus crispatus strengthens the cells that protect your gut microbiome.

Pros
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    Safe for pregnant women
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    Protects heart health
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    Contains lactobacillus strains
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    Boosts energy levels
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    Supports regular bowel movement
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    Approved for digestive survivability
Cons
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    Very expensive
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    Unsuitable for those under 18
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    Requires a subscription

#7 Amy Myers MD Probiotics – Best for gut inflammation 

Amy Myers MD Probiotics logo
Our rating:
3.7
stars
  • Boosts intestinal microecology
  • Fights stubborn inflammation in the gut
Learn More

Amy Myers probiotics are best for treating inflammatory bowel disease and irritable bowel syndrome. Several ingredients, like lactobacillus acidophilus and bifidobacterium lactis, can help your body reduce inflammation in the gut. 

Research proves that lactobacillus acidophilus protects the gut lining against toxins. It almost creates a barrier in your digestive tract that keeps good bacteria thriving. 

On the other hand, bifidobacterium lactis absorbs important nutrients and minerals from food, leading to better gut health. Your body needs vitamins to boost digestive enzymes and relieve common symptoms of leaky gut syndrome. 

People with inflammatory bowel diseases may need that extra support to prevent inflammation from damaging their digestive health. The same goes for those with a leaky gut, as this condition can cause intestinal epithelial barrier dysfunction.

Pros
  • checkmark
    Replenishes the intestinal lining
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    14 active probiotic strains
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    May support weight loss
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    Strengthens lactose digestion
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    Reduces constipation
  • checkmark
    Regulates normal bowel function
Cons
  • checkmark
    Reports of heart palpitations
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    Can cause gas and bloating
  • checkmark
    Unsustainable packaging

Comparing the Best Probiotics for Leaky Gut

Comparison Winner: Bioma
4.5
stars
4.2
stars
4.3
stars
4.0
stars
3.7
stars
3.9
stars
3.8
stars
Brand
Bioma
Probulin
Klaire Labs Ther-Biotic
Just Thrive Probiotic & Antioxidant
Amy Myers MD Probiotics
Align 24/7 Digestive Support
Seed
Pros

Reduces bloating

Improves digestion

Less flatulence

No gut discomfort

Decrease inflammation

Reduces hunger cravings

Increases energy levels

Preserves muscle mass 

Contains lactobacillus and bifidobacteria

Supports immune health

Delayed-release capsules

No refrigeration

Reduces bloating

Helps to prevent cramps  

Strengthens intestinal barrier integrity

Suitable for IBS Can reduce chronic fatigue and brain fog

No artificial ingredients

Improves digestion

Regulates bowel movement

Reduces excess gas

Improves nutrient absorption

Boosts your energy levels

Suitable for keto and vegan diets

Promotes clear skin

Relieves constipation

May relieve stomach ache 

Supports lactose digestion

Can boost fat burning

Reduces gut inflammation

14 bacteria strains

Reduces constipation

Regulates bowel movement 

Supports good digestion Inexpensive supplement

Reduces bloating and gas

Boosts immunity

Suitable for IBS symptoms

Can prevent constipation 

Safe for pregnant women

Protects heart health

Contains lactobacillus strains

Boosts energy levels

Supports bowel movements

Approved for digestive survivability 

Cons

Possible minor side effects like gas

Results can differ from person to person

Requires consistent use 

Can be expensive in the long term

Some users report poor packaging

Could cause constipation 

Needs refrigeration

Not suitable for those on a budget

Not much science-based evidence on their website  

Some side effects like bloating

Has to be taken with food

Expensive shipping 

Reports of heart palpitations

Potential side effects like bloating and gas

Unsustainable packaging 

Contains one strain

Reports of people getting stomach pain

Can trigger nausea 

Subscription-based

Not suitable for people under 18

Very expensive 

How We Tested the Products

Our team believes that supplements need to be reliable, natural, inexpensive, and effective. People should buy probiotics knowing they work to reduce the common leaky gut symptoms. Before adding these supplements to the list, we carefully examined a few dominant factors. 

Below are some factors we considered when choosing the products: 

Quality

We chose high-quality products that have comprehensive formulas and packaging. Everyone deserves to put their money toward the most natural supplements in today’s market. Quality also includes manufacturing processes, versatility, and efficiency of capsules in the stomach. 

Effectiveness 

Probiotic supplements need to work, right? Therefore, we chose products that contain tested ingredients and have positive reviews. You’re the only person who can judge whether they’re effective for your health, but most active strains in these probiotics are good for leaky gut. 

Price

Not everyone can afford expensive supplements in the long term. Our team understands that people need something sustainable in their routines. The list of probiotics contains inexpensive options that support those with leaky gut syndrome and inflammatory bowel disease.

Brand reputation 

Brands should care more about a customer’s health rather than money. 

We studied each website to gain a sense of brand mission and transparency with product creation. Fortunately, every supplement on the list has been made by reputable brands that take value in their probiotics. 

A Word From Our Medical Team

Probiotic supplements should treat leaky gut symptoms and not worsen the condition. Therefore, it’s important to study the ingredients list before buying a product. You don’t want to fuel your body with inactive bacteria strains or preservatives that actually promote leaky gut.

Consider trying gut health hacks to relieve leaky gut. Some of them include drinking more water, consuming enough fiber, exercising regularly, and avoiding processed foods. A study found that regular exercise strengthens your intestinal environment by promoting microflora diversity.

Remember that probiotics might not work for everyone. If you get too many unwanted side effects, consult with a medical professional about finding the right supplements. You might need stronger probiotic strains or capsules that are specifically designed to treat leaky gut syndrome.

Conclusion

If you’ve been diagnosed with leaky gut syndrome, it doesn’t mean you must suffer through it and deal with discomfort for the rest of your life.

Probiotic supplements with the appropriate formula can substantially improve your gut health. Bioma, Probulin, and Klaire Labs Ther-Biotic are the top contenders for relieving leaky gut syndrome.

Just make sure to consult with your doctor before taking supplements so that you get a suitable treatment for your condition.

Written by Edibel Quintero, RD
Edibel Quintero is a medical doctor who graduated in 2013 from the University of Zulia and has been working in her profession since then. She specializes in obesity and nutrition, physical rehabilitation, sports massage and post-operative rehabilitation. Edibel’s goal is to help people live healthier lives by educating them about food, exercise, mental wellness and other lifestyle choices that can improve their quality of life.
The article was fact checked by Rosmy Barrios, MD
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HR_author_photo_Edibel
Written by Edibel Quintero, RD
HR_author_photo_Rosmy
Fact checked by Rosmy Barrios, MD
Last update: September 6, 2023
7 min read 1120 Views 0 Reviews
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