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Home arrow Health arrow Gut Health arrow Bio Complete 3 Review: Everything You Should Know

Bio Complete 3 Review: Everything You Should Know

Written by Edibel Quintero, RD
Dr. Donika Vata
Fact checked by Donika Vata, MD
Last update: August 31, 2023
12 min read 739 Views 0 Reviews
clock 12 eye 739 comments 0

Struggling with gut health issues can be discouraging and frustrating, but there are ways to improve. Can Bio Complete 3 help you?

Bio Complete 3 Review - Everything You Should Know

How do we vet brands and products? Learn more.

Is your gut healthy? A healthy gut is essential for a strong immune system, healthy digestion, and a balanced microbiota. You may have heard of the gut as the “second brain” because of its innate connection to your mental well-being.

Poor gut health could be to blame if you’ve ever struggled with common issues like fatigue, low mood, or digestive problems. Bio Complete 3 offers a way to support optimal gut health, promote good gut bacteria, and benefit your mental health. 

But does Bio Complete 3 really work? In this review, I assess everything you need to know about the supplement. Read on to find out if this supplement is worth your while.

What Is Bio Complete 3?

GundryMD Logo
Our rating:
  • Three biotics combined for optimal gut function
  • Easy to swallow
  • Aids good bacterial growth
  • Reduces unhealthy food cravings
Learn More
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    Third-party tested
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    Helps weight management
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    Suppresses cravings for sweets
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    No medical reviews
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    No guarantee of effectiveness

Bio Complete 3 is a digestive health gut supplement created by Gundry MD. Gundry MD is renowned for its selection of supplements and skincare products targeted at gut health.

Combining prebiotics, probiotics, and prebiotics, Bio Complete 3 is a complete gut health supplement that promotes a healthy digestive system and supports your gut microbiome and the healthy bacteria your gut needs.

Bio Complete 3 can support healthy digestion and weight management because its combination of probiotics can support the natural flora in your gut. The prebiotic blend helps eliminate fatigue, while the postbiotic minimizes unhealthy food cravings, making weight management easier for many.

Who is Bio Complete 3 for?

There are many reasons to consider Bio Complete 3 as a nutritional supplement. Here’s an overview of why I’m most likely to recommend Bio Complete 3 to clients based on their needs. If you identify with any of these issues, there’s a chance that Bio Complete 3 could benefit you.

  • Weight management. Taking Bio Complete 3 can help you lose weight. Anyone struggling with weight gain will appreciate the supplement’s advertised ability to reduce cravings for unhealthy foods.
  • Irritable bowel syndrome. If you’ve been struggling with acidity and painful bowel movements, Bio Complete 3 could help. The Gundry MD Bio Complete 3 product page suggests results like “smooth, comfortable digestion.”
  • Fatigue and low mood. Low energy levels make us feel down. Bio Complete 3 aims to provide an “abundance of youthful energy” that could put an end to tired, depressive days.

Your gut health is essential to a healthy life, but it’s hard to trust a product that claims to improve gut health, support healthy digestion, and lead to weight loss. This is one of the reasons I decided to review Bio Complete 3.

Why I Decided to Test Bio Complete 3

I decided to review Bio Complete 3 to investigate the features that Gundry MD claims in its advertising. I wanted to know if Bio Complete 3 could really improve my patients’ intestinal health, relieve their irritable bowel syndrome, or act as a diet aid for clients struggling with weight management.

Typically, a gut health supplement backs up its claims with clinical research. However, the Gundry MD Bio Complete 3 supplement does not provide any clinical research on the effectiveness of its product. 

Instead, they use the disclaimer: “Every individual is unique. As such, your results may vary.” This vagueness may keep Gundry MD legally safe, but it leaves questions unanswered.

The Gundry MD Bio Complete 3 product makes many claims and has third-party research. It seemed like a prime candidate for a thorough review to see if it can help with gut health. 

It could be the perfect solution for many if it alleviates problems such as leaky gut syndrome, irritable bowel syndrome, and weight management.

How Does Bio Complete 3 Work?

Gundry MD Bio Complete 3 is a triple-action supplement designed to support beneficial gut bacteria and help you achieve a healthy gut. The combination of three biotic ingredients restores balance to the gut microbiota, fighting off harmful bacteria and protecting good gut bacteria.

The ingredients increase probiotic levels, creating an abundance of beneficial bacteria throughout your gut and digestive tract. Increased prebiotic levels fuel the gut and increase energy levels. 

Finally, the postbiotic aspect of Bio Complete 3 increases butyrate levels in the gut, making it stronger and less likely to struggle with unhealthy cravings.

Probiotics are essential for restoring the bacterial balance in your gut, especially if you’ve been dealing with an illness or treatment that has weakened your body’s defenses. When you consume a product with probiotics that make it to your gut alive, it produces healthy bacteria that restore your strength.

Probiotics are a form of good bacteria that make it easier for your microbiome to fight off bad bacteria, so you’re less likely to get sick or struggle with gut problems.

How to take Bio Complete 3

The recommended dosage for Gundry MD Bio Complete 3 is two scapsules twice daily for a total of four daily capsules. Gundry MD states that it’s best to take Bio Complete 3 before a meal. 

For most users, this means taking two with breakfast and two with dinner. This distribution is intended to get the full effects of Gundry MD Bio Complete 3 throughout the day. Professionally, I find this very convenient, as many patients report having difficulty remembering to take their medication regularly.

What are the Key Ingredients of Bio Complete 3?

The ingredients provided on the Gundry MD Bio Complete 3 product page are described as three key blends – probiotic, prebiotic, and postbiotic. They break down like this:

#1 Prebiotic blend: SunFiber®

SunFiber acts as the prebiotic component of Bio Complete 3. Owned by Taiyo International, Inc, SunFiber is a partially hydrolyzed guar gum intended to add dietary fiber to supplements. In this medical review, the authors proposed a minimum daily intake of 20,000mg of SunFibre to have a measurable impact. 

However, Gundry MD Bio Complete 3 contains only 200mg of SunFibre per serving. There is no evidence available online or on the Gundry MD product page to suggest the value of a 200mg dose of SunFibre as a dietary supplement.

#2 Postbiotic blend: Corebiome®

Tributyrin is the generic name for CoreBiome. It’s a postbiotic ingredient intended to increase gut health by ensuring the strength of the lining itself. The product page on the Compound Solutions website, the creators of CoreBiome, lists no active ingredients in the probiotic. 

The website claims that CoreBiome has applications for improving digestive health and weight management, but it’s difficult to assess the validity of these claims without research or specific ingredients.

#3 Probiotic blend: ProDura®

ProDura is a probiotic called Bacillus coagulans under the trademarked name owned by UAS Laboratories LLC. Bacillus coagulans have been used in clinical research and appear to improve digestive tract health, although not in the same dosages found in Bio Complete 3. 

In this study, for example, patients were given 333.33mg of Bacillus coagulans. For context, Gundry MD Bio Complete 3 only has 22mg of ProDura per each two-capsule serving size.

There are no studies surrounding the effectiveness of bacillus coagulans in such low dosages, making it difficult to ascertain the value of ProDura as an ingredient.

Other ingredients included in the Gundry MD Bio Complete 3 product include:

  • Silica
  • Microcrystalline Cellulose
  • Magnesium Stearate
  • Hydroxypropyl Methylcellulose

One immediate positive is that Bio Complete 3 uses natural ingredients to create probiotic supplementation that can lead to a healthy gut. 

What are the Key Ingredients of Bio Complete 3

What I Liked About Bio Complete 3: 6 Main Benefits

Here’s a breakdown of the 6 main benefits of using Bio Complete 3.

#1 It boosts energy levels

Taking Bio Complete 3 can significantly increase your energy levels. When your gut is healthy, your body doesn’t have to expend as much energy on it. As a result, you may find that fatigue is a problem of the past. 

I find that many patients who experience fatigue can alleviate their symptoms without prescribed medical intervention. For example, changes in diet and exercise can make a big difference. Similarly, the probiotic ingredients in Bio Complete 3 could also increase energy levels.

#2 It may promote weight loss

The combined ingredients make this a supplement that promotes weight loss because of their effect on your gut. When your gut has a healthy lining and a strong microbiome, you may crave sugary snacks and fatty foods less. Reduced cravings make it easier to create healthy habits and build a healthier lifestyle.

#3 It’s third-party tested

Third-party testing adds confidence to the claims Bio Complete 3 makes about its capabilities. Positive feedback from objective parties makes this supplement more appealing than those without. Industry specialists have developed this supplement, suggesting a high-quality product.

#4 It’s easy to take

Some supplements are complicated to take or large and uncomfortable to swallow. However, one dose of this supplement is two small capsules that you can take before breakfast and dinner for a daily dose. Setting times makes it easier to remember to take your supplements and stay consistent.

#5 You get a money-back guarantee

Perhaps the best feature of this supplement is its 90-day money-back guarantee. As the product page explains, everyone is different, and the supplement will not provide the same relief for everyone. If you try it for 90 days and aren’t satisfied, you can get a full refund.

#6 You’re unlikely to experience side effects

Because of the natural ingredients used in Bio Complete 3, it’s highly unlikely that you will experience any negative side effects. This is a significant benefit, especially when compared to available supplements that are more like diuretics. Even if you don’t get the results you want, it’s a relief to know that the side effects are minimal.

The Downsides of Bio Complete 3

Next, it’s time to review the downsides of this supplement. Understanding the downsides of any supplement is essential to making an informed decision about whether it’s right for you.

#1 You may need a month to notice results

As with most dietary changes, it takes time to feel the effects of this supplement. Some users report feeling different in a week, but it can take a month or more to see the results. Fortunately, the 90-day money-back guarantee puts you in a good position to judge whether or not it works for you.

#2 The amount of CFU is unknown

Colony-forming units (CFU) measure probiotics, indicating the number of viable cells contained within a probiotic. However, Gundry MD Bio Complete 3 doesn’t provide any information about the CFU of the product. 

This isn’t an overwhelming concern for many, but it raises questions about the product’s effectiveness. Furthermore, without a clear CFU measurement, it’s impossible to thoroughly compare Bio Complete 3 to other probiotics.

#3 Only one strain of probiotic included

Another similar drawback is that Bio Complete 3 uses only a single probiotic strain. For context, the popular health food kefir can contain up to 61 strains of probiotic bacteria and yeasts. Again, this isn’t a significant concern for everyone, but it does mean that Bio Complete 3 may be less effective than similar supplements.

#4 Only available on the official website

Most over-the-counter supplements are readily available in any drugstore. From a medical perspective, I understand that many patients prefer the flexibility of being able to purchase their supplements from a variety of physical stores. 

However, this product is only available through the Gundry MD website. Previously listed on Amazon, it is now a website-exclusive product. It’s also an expensive product.

Pricing of Bio Complete 3

As we’ve noted, Bio Complete 3 is expensive. A single bottle contains 60 capsules and costs $69.95. Following the recommended dosage means that this bottle can last 15 days, just over two weeks. 

Users can purchase 3 bottles at a time for $188.85 or 6 for $353.70. For those interested in trying Bio Complete 3, opening a free Gundry MD account reduces the cost of a single bottle to $49.95.

What Do Others Think About Bio Complete 3?

The reviews on the Gundry MD website and other third-party review sites are mostly positive, with some less than enthusiastic. 

Most users report losing their cravings for sweet snacks, feeling less bloated, and having more energy. Calmer stomachs and regular bowel movements are common results of using Bio Complete 3 for most users.

The one-star reviews mostly mention the supplement having no effect or causing a bloated feeling. Fortunately, they don’t mention any serious or lasting side effects.

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Bio Complete 3 vs. Other Probiotic Brands

Here’s our breakdown of how Bio Complete 3 compares to other probiotic brands available.

Comparison Winner: Bioma
Biotics 8
Bio Complete 3

Reduced hunger cravings

Increased energy levels

Stops diarrhea and constipation

Boosts gut health

Increases T-levels for men

Improved digestion

Third-party tested

Can relieve gut health issues

Can aid weight management


Could cause constipation

Can cause stomach upsets

Inconsistent results

Possible allergic reactions

Can cause flatulence

Men’s only product

Only available through the main site

Can cause digestive discomfort


Can cause bloating

No medical reviews

No guaranteed effects


Is Bio Complete 3 FDA-approved?

As of the time of writing, Bio Complete 3 does not have FDA approval.

Is Bio Complete 3 legit?

It seems that Bio Complete 3 has a legitimate effect on many users. Medical professionals were involved in its creation, and it used third-party testing.

What are the side effects of Bio Complete 3?

There are no serious side effects from taking Bio Complete 3. However, users have reported experiencing stomach cramps, gas, bloating, nausea, and indigestion as side effects.

Where can you buy Bio Complete 3?

The only place to buy Bio Complete 3 is on the Gundry MD website.

How I Tested Bio Complete 3

Before I write a review, I always test a product to determine its effectiveness and quality for potential patients. I used the following criteria to assess Bio Complete 3 as a product.

Quality 8/10

Bio Complete 3 uses probiotics, prebiotics, and postbiotics with professional expertise to create a high-quality supplement. Medical professionals were behind the development of the supplement, using high-quality ingredients in its creation. Because of the quality ingredients and manufacturing process behind Bio Complete 3, I have awarded it with an 8/10 for its overall quality.

Effectiveness 7/10

For this criteria, I examined reviews from Bio Complete 3 users and sought out any medical studies supporting the use of the ingredients. Most of the Trustpilot reviews for Bio Complete 3 are positive, but there are some users who found the product ineffective. 

There’s a distinct lack of medical support for the effectiveness of the prebiotic ingredients in the dosages in Bio Complete 3, dragging this score down.

Price 6/10

There’s no easy way to discuss the price of Bio Complete 3 without addressing its high price tag. There are definitely cheaper supplements on the market, although whether they are of higher quality is debatable. Regardless, this product’s price tag weighs down its overall score.

Brand reputation 7/10

Gundry MD is a widely recognized brand, not only for Bio Complete 3 but also for its other products, such as Total Restore, which targets leaky gut, and its skincare products. For this reason, Gundry MD receives a reputable 7/10 for its brand value.

A Word From Our MD

Always consult a healthcare professional before starting any new dietary supplement such as Bio Complete 3. Follow the recommended dosage of two capsules twice daily before meals. Users may find that it takes up to 90 days to experience the advertised results.

Taking Bio Complete 3 can reduce digestive problems and promote intestinal health. For best results, use this supplement as part of a healthy diet and active lifestyle. There are several ways to keep your gut in good shape before turning to supplements for help.

Firstly, stay hydrated throughout the day by consistently drinking water. You should also aim to get at least 7 hours of sleep each night.

If you experience adverse effects from taking the supplement, either reduce your dosage or stop taking them and contact the supplier or a medical professional for advice.

Conclusion: Is Bio Complete 3 Worth Your Money?

I believe that although Bio Complete 3 is an expensive supplement, it is worth the money. If it works for you, you can expect smoother digestion and increased energy levels within a month or two. Likewise, if it doesn’t work for you, you can easily get your money back within 90 days and continue to explore the supplement market.

If you struggle with gut health, this product could be the perfect supplement that brings a sense of peace and rejuvenation to your daily life. However, it may not work for everyone, and we have reviewed other supplements on the market for those who might prefer something else.

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Written by Edibel Quintero, RD
Dr. Donika Vata
Fact checked by Donika Vata, MD
Last update: August 31, 2023
12 min read 739 Views 0 Reviews
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