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Mental Health
NooCube Review: Does It Truly Enhance Brain Productivity?
Mental Health

NooCube Review: Does It Truly Enhance Brain Productivity?

NooCube claims to improve cognitive function and general brain health. Is this true, or is it just another exaggerated attempt to sell a brain booster? Stick with us as we deep dive into the details of NooCube.

noocube review
HealthReporter edit

Among the many nootropic-based products that have graced the health and pharmaceutical market in 2022, NooCube claims to check all the boxes needed to qualify as a top-tier brain booster. But how true is that? 

Today, we do a full NooCube review to find out if these brain pills support brain health. Is this nootropic supplement as good as the reports claim? 

Will you undergo improved productivity, or is this another marketing deception?

What Is NooCube?

  • Improves mental energy, focus, and memory

  • Natural ingredients
  • Clinically supported
  • GMO, soy, and grain-free
Our rating:
Learn More
  • Non-GMO
  • Caffeine-free
  • Gluten-free
  • Contains natural ingredients
  • Halts neurodegenerative disorders
  • Enhanced mental clarity and concentration
  • Heightened cognitive awareness and memory
  • Improved reaction
  • Not suitable for everybody
  • Limited availability (strictly limited to the company website)
  • Takes a while to feel the effects

NooCube is an all-new brain supplement that not only functions in maintaining brain health but also serves to enhance brain function and overall cognitive function. It features a combination of all-natural ingredients, amino acids, and pro-brain vitamins.

Additionally, it helps reduce stress levels, improve mood, reduce brain regeneration, and prevent mental health issues. 

NooCube achieves these health benefits through a mix of herbal extracts, vitamins, and minerals, including alpha GPC, huperzine A, and cat’s claw – all of which have been clinically studied for efficacy.  

These ingredients work together to support cognitive functions and promote brain health by increasing acetylcholine levels and boosting blood flow to the brain. NooCube also contains B vitamins essential for energy production and nerve function. 

As such, you will be able to think more clearly, learn new information more easily, and become more productive. NooCube is also non-addictive. Still, considering the compounds found in the supplement, users may experience slight side effects and allergic reactions. 

These side effects include headaches, stomach aches, and nausea. However, manufacturers of this nootropic maintain that sticking to the recommended dose negates the side effects.

Does NooCube Really Work?

While it may be hard to buy into the fact that you can boost brain function, NooCube claims its supplement improves mental health. 

On the whole, there is no denying that NooCube contains some powerful ingredients. While the evidence does support the health benefit claims made by NooCube, it is important to remember that no supplement can magically make you smarter overnight. 

As such, it would be best to approach this supplement from a realistic standpoint. That is because this supplement can only enhance your cognitive function if you’re already using it effectively.

How Does NooCube Work?

The grounds on which the supplement performs its brain-enhancing wonders are quite old, given that nootropics have existed for a long time. 

The supplement accounts for an increased supply of oxygenated blood and nutrient absorption in the brain, sparking the production of varying neurotransmitters. 

The variety of herbs, amino acids, and vitamins present in NooCube all support increased levels of learning, concentration, memory, and problem-solving. Conversely, its antioxidant properties also help reduce age-related inflammation and cell damage. 

Simply put, one part of the ingredients caters to heightened cognitive performance, while the other part caters to age-related cognitive decline, memory loss, and mental lapses.

Is NooCube Safe?

Yes, NooCube is relatively safe to consume. While there are a few side effects, such as nausea and headaches, there are no reported cases of adverse reactions while taking the supplement. 

How to Take NooCube?

Manufacturers of NooCube claim that you do not need a prescription to take the supplement. A glass of water is all you need.

Regarding the dosage, you should start with two capsules with breakfast to be on the safer side.

You can upgrade to 4 capsules if that does not yield the desired results. However, that should also be your limit. 

NooCube Nutritional Label

noocube ingredients list

Source: https://noocube.com/

NooCube Ingredients

NooCube certainly is not short of powerful ingredients. After all, that is the only way to invoke such positive mental change. The NooCube formula encompasses 13 all-natural ingredients proven to positively influence brain health. 

Let’s look at each of the 13 ingredients to see what they do and how this mix promotes brain health. 

#1 Alpha GPC (Glycerylphosphorylcholine)

The primary active ingredient in NooCube is alpha GPC, with about 50mg. Alpha GPC is a precursor to the neurotransmitter acetylcholine. 

The neurotransmitter acetylcholine helps foster communication between brain cells, especially regarding cognitive functions such as memory, focus, and learning. A boost in the brain’s natural supply of neurotransmitters will improve memory, mental speed, and attention. 

Similarly, aside from cognitive improvement, there are ongoing clinical trials to determine the efficacy of alpha GPC as a treatment for Alzheimer’s disease and vascular dementia. 

#2 Huperzine serrata (0.5% huperzine-A)

NooCube contains 20mg of huperzine-A. Huperzine-A is an alkaloid compound derived from the huperzine serrata (Chinese club moss) plant. 

For the most part, it has been used for centuries in traditional Chinese medicine to treat a variety of conditions, including fever and inflammation. 

However, huperzine-A is also known as an acetylcholinesterase (AChE) inhibitor, which means it helps prevent the breakdown of acetylcholine in the brain. This is important because acetylcholine is a neurotransmitter that plays a role in memory and learning. 

Just like with alpha GPC, studies show that huperzine-A may improve cognitive function in people with Alzheimer’s disease or other forms of dementia. It has also been shown to be helpful in treating attention deficit hyperactivity disorder (ADHD).

#3 Cat’s claw

Cat’s claw (Uncaria tomentosa) is a woody vine that grows in the tropical rainforests of South and Central America. NooCube contains a concentrated 4:1 cat’s claw extract.

According to research, this powerful brain nutrient helps decrease brain plaques and tangles. Likewise, the research suggests that the plant may help protect the brain from age-related damage and improve symptoms in people with Alzheimer’s disease. 

In addition to its neuroprotective benefits, cat’s claw is also a potent anti-inflammatory and immune booster. It is commonly used to treat arthritis, allergies, and asthma. 

#4 Oat straw

NooCube contains a 10:1 ratio of oat straw extract. Oat straw extract is one of the oldest known brain enhancers, dating all the way back to the middle ages. 

The active ingredient in oat straw is Avena Sativa, a phytochemical type that offers various benefits, including increasing blood flow to the brain and enhancing cognitive abilities.

A small study published in the journal Nutraceuticals found that the extract can increase a person’s responsiveness, boost memory, and improve attention span. 

It showed that participants who took oat straw extract experienced increased alpha-2 activity compared to those who took a placebo. Alpha-2 waves in the brain are associated with deep relaxation and focus. 

As such, when alpha-2 levels are increased, it is easier to maintain concentration and avoid distractions. 

To put things into a much better perspective, the effects of oat straw extract are similar to those of caffeine but without the jitteriness or agitation that sometimes accompanies caffeine consumption. 

Lastly, the extract contains antioxidants such as avenanthramides that help lower the risk of cardiovascular diseases, diabetes, and malignancies.

#5 Bacopa monnieri

Bacopa monnieri is a plant used for centuries in Ayurvedic medicine to support cognitive function. Also known as Brahmi, this herb is traditionally taken as a brain tonic to help boost memory, concentration, and mental clarity. 

According to recent research, bacopa monnieri possesses cognitive-enhancing effects, one of which improves working memory and cognitive processing speed in healthy adults. 

It does this by suppressing acetylcholinesterase (AChE) activities, enhancing cholinergic function. This, in turn, improves cognitive performance.

Other studies have shown that bacopa monnieri can help reduce stress and anxiety, both of which can impact cognitive function. 

#6 Resveratrol 99%

Present in 14.3mg, resveratrol is a type of polyphenol, a class of phytonutrients. It is found in the skin of red grapes and other fruits and vegetables, such as raspberries, mulberries, and blueberries. 

Polyphenols are antioxidants, which means that they help protect cells from damage. Resveratrol has been shown to have several health benefits, including reducing inflammation, protecting against heart disease and stroke, and even slowing the aging process. 

In addition, resveratrol is thought to boost the immune system and help fight cancer. However, as much as evidence exists that backs up these claims, there is a need for more clinical trials to quantify its impact on overall health.

#7 Pterostilbene

Just like resveratrol, pterostilbene is a powerful antioxidant that can be found in certain berries, including blueberries, grapes, and cranberries.

Both compounds share a similar chemical structure, offering a wide range of potential health benefits, including enhancing the brain’s neurotrophic factors, improving learning and memory, decreasing cognitive decline, reducing inflammation, and lowering blood sugar levels. 

However, unlike resveratrol, pterostilbene can cross the blood-brain barrier, making it more effective at fighting free radicals in the brain. As such, NooCube only contains 140 micrograms of this compound. 

Additionally, pterostilbene has been shown to boost levels of “good” HDL cholesterol and protect LDL cholesterol from oxidation. These effects make pterostilbene a promising natural remedy for heart disease. 

#8 Lutemax

Lutemax is a food supplement that contains lutein and zeaxanthin, two nutrients essential for eye health. Likewise, studies affirm that lutemax can improve learning abilities, focus, and overall brain health.

Lutein is a carotenoid pigment found in high concentrations in the macula, the central area of the retina. Zeaxanthin is another carotenoid pigment that is located in the macula as well as in the lens of the eye. 

Both lutein and zeaxanthin are powerful antioxidants, and they help protect the eyes from damage caused by ultraviolet light. 

Lutemax also contains L-carnitine, an amino acid that helps transport fatty acids into the mitochondria. L-carnitine has been shown to improve mitochondrial function and reduce the risk of age-related vision problems.

#9 L-tyrosine

L-tyrosine is an amino acid that plays a vital role in producing protein and nerve function. NooCube contains 250mg of L-tyrosine.

According to research, poor sleeping habits and negative environmental factors can affect the levels of certain neurotransmitters, such as dopamine and norepinephrine. 

These neurotransmitters are responsible for mood, focus, and energy levels while inducing self-control in ADHD patients and lowering anxiety, stress, and depression levels. 

L-tyrosine intake can help the body produce these neurotransmitters, allowing the body to continue optimal cognitive functions, as well as improve reaction time during times of stress.

In fact, research affirms that L-tyrosine has a high potential as a treatment for ADHD due to its ability to increase serotonin and dopamine levels. As such, experts include it in Ritalin and Adderall treatments to reduce the side effects of these medications.

#10 L-theanine

NooCube contains 100mg of L-theanine. L-theanine is an amino acid common in green tea and certain mushrooms. This water-soluble compound is best known for its calming and relaxing effects. As such, it will improve sleep quality greatly. 

Concerning cognitive benefits, L-theanine helps with focus and attention. Researchers attribute these benefits to an increase in GABA levels (this neurotransmitter is responsible for relaxation).

L-theanine also inhibits the release of stress hormones and can help reduce anxiety and promote relaxation. As such, people with schizophrenia get better sleep as it reduces glutamate levels. 

Furthermore, people with bipolar disorder and PTSD benefit positively as it helps with gene expression and neurotransmitter management.

#11 Vitamin B1

Vitamin B1, also known as thiamine, is a water-soluble vitamin that is involved in a variety of cellular processes. It helps convert glucose into energy, supports nerve function, and aids in the formation of red blood cells. 

Vitamin B1 deficiency can lead to beriberi, a condition characterized by weakness and muscle pain, heart problems, and digestive disorders. In severe cases, it can be fatal. Fortunately, beriberi is rare in developed countries due to improved nutrition and food fortification programs.

#12 Vitamin B7

Vitamin B7 (biotin) is a water-soluble vitamin that is a part of the B complex family. This vitamin’s role is crucial as it plays a huge part in energy metabolism and fatty acid synthesis. Likewise, it helps with keeping skin, hair, and nails healthy. 

While biotin deficiency is rare, it can occur in people with poor diets or certain medical conditions. Symptoms of biotin deficiency include hair loss, skin rashes, and fatigue.

#13 Vitamin B12

Vitamin B12 is present in 2.7 micrograms in NooCube. According to the recommended dietary allowance (RDA), adults need to consume 2.4 micrograms of vitamin B12 daily. 

You can find the vitamin naturally in some foods while it comes added to other foods. Vitamin B12 is also available as a dietary supplement and prescription medication. 

Vitamin B12 exists in several forms and contains the mineral cobalt, so it is also known as cobalamin. 

Vitamin B12 is involved in many important processes in the body. It helps prevent damage to neurotransmitters, improve energy levels, and boost mood. It is also a critical factor in DNA synthesis, red blood cell formation, and neurological function. 

When taken at recommended levels, vitamin B12 is generally considered safe. However, excessive vitamin B12 can cause side effects such as diarrhea, abdominal cramping, and bloating. 

What Is the Price of NooCube?

NooCube offers 3 distinct options on their website. With each option, you get free global shipping, a free brain guide, and free bottles.

One-month supply, the cheapest option of the three, retails at $59.99. You get 60 capsules with this option. A 3-month supply, which is the popular option, retails at $119.99, and you get 180 capsules. Lastly, the biggest 6-month supply retails at $179.99, and you get 360 capsules.

You also get a 60-day money-back guarantee from NooCube, regardless of which option you purchase. 

NooCube vs. Mind Lab Pro

While NooCube claims to be the best amongst its peers, other brands boast of their superiority. Mind Lab Pro is another top-ranking brain supplement in today’s market. 

While doing this review, we decided to pit both supplements against each other to see which is worth investing in. Take a look.

Mind Lab Pro

Natural ingredients, including Lutemax® 2020

Clinically supported

GMO, soy, and grain-free

Improves mental energy, focus, and memory

60-day money-back guarantee with free global shipping

Natural ingredients

Clinically supported

Good value for money

Improves focus, mood, and memory

Fast shipping

Only available on the company website

No free shipping

Quite expensive

No money-back guarantee

Mind Lab Pro
Overall Rating

Natural ingredients, including Lutemax® 2020

Clinically supported

GMO, soy, and grain-free

Improves mental energy, focus, and memory

60-day money-back guarantee with free global shipping

Natural ingredients

Clinically supported

Good value for money

Improves focus, mood, and memory

Fast shipping


Only available on the company website

No free shipping

Quite expensive

No money-back guarantee

As it stands, NooCube has a slight edge over Mind Lab Pro. While both offer similar benefits, NooCube is cheaper and has the option of free shipping and a 60-day money-back guarantee.


Here are some frequently asked questions about NooCube pills. 

Where can I buy NooCube?

You can only get the supplement on the official website. The manufacturers also provide a 60-day money-back guarantee upon any purchase made on the website.

Are nootropics legal to use?

Yes, most nootropics found on a regular basis are legal to use globally.

How long does NooCube work?

It typically takes between 30 to 45 minutes for you to notice any effects. The effects usually last anywhere from 8 to 10 hours, depending on the dosage.

However, it may take as long as a week to notice a long-term impact. Still, it is worth noting that the effect differs from person to person.

How We Tested

Over the course of our NooCube review, the primary goal was to ascertain if the supplement held true to the claims. That way, potential users get access to quality information to make an informed decision.

On that note, we centered our research and, ultimately, review on four key categories: quality, effectiveness, price, and brand reputation. Here are our results.

Quality 8/10

Employing a dietary supplement to aid cognitive enhancement is no minor issue by any metric. As such, the quality of ingredients must be top-tier to ensure safety. 

NooCube is a high-quality supplement from the best, most commonly used nootropics globally. Manufacturers of the supplement claim to have tested the ingredients and deemed them safe enough to make a consumable product.

Effectiveness 7/10

While effectiveness is just as paramount as quality, it is somewhat foolish to conclude that a product of this nature would work instantaneously. That is because most of the ingredients are potent compounds; the priority would always be safety. 

While NooCube does work, it takes about 30–45 minutes for the effects to kick in. Likewise, its long-term benefits take up to a week to manifest. However, users claim to experience significant improvements after use.

Overall, the science behind the supplement is lacking, considering that not much is known about the efficacy of nootropics. 

Price 7/10

NooCube is one of the cheaper brain enhancers available. With three options available for purchase, it is budget-friendly, and you get free global shipping. 

Brand reputation 9/10

NooCube is manufactured by Wolfson Brand, which happens to be one of the best manufacturers in the health and fitness market (their products certainly speak wonders for the brand).

While Wolfson Brand is located in Cyprus (as with other brands swayed by tax-evasion opportunities), NooCube remains manufactured in FDA-approved facilities in the US and all around Europe. 

A Word From Our RD

NooCube is one of the most revered nootropic-based supplements currently on the market. Its ability to clear brain fog, correct mood disorders, protect brain cells, and enhance cognition makes it valuable to everybody.

So, while NooCube is safe for most people to take and helps improve mental health and brain functioning, it is best to tread cautiously.

As such, you should speak with a qualified healthcare provider before taking NooCube to confirm if you are suited for it, especially if you are on mental health medications.


NooCube features a functional formula through a combination of natural ingredients designed to keep you focused and at the top of your game. It is specially crafted for men and women from all walks of life, from parents to athletes to older adults aged 55 and above. 

However, science shows that taking brain enhancers alone will not necessarily yield the level of results you desire. For that, you need to eat healthily, exercise, practice stress management, and get enough sleep.

Written by
Edibel Quintero is a medical doctor who graduated in 2013 from the University of Zulia and has been working in her profession since then. She specializes in obesity and nutrition, physical rehabilitation, sports massage and post-operative rehabilitation. Edibel’s goal is to help people live healthier lives by educating them about food, exercise, mental wellness and other lifestyle choices that can improve their quality of life.
Fact checked by Rosmy Barrios, MD
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