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Home arrow Health arrow Mental Health arrow NooCube Review: Does It Truly Enhance Brain Productivity?

NooCube Review: Does It Truly Enhance Brain Productivity?

Written by Edibel Quintero, RD
Fact checked by Rosmy Barrios, MD
Last update: October 10, 2023
17 min read 1323 Views 0 Reviews
clock 17 eye 1323 comments 0

Are you wondering if the NooCube nootropic supplement is a good option to improve your brain health? Read my detailed review of this product to find out.

NooCube Review - Does It Truly Enhance Brain Productivity

How do we vet brands and products? Learn more.

While exercise and a balanced diet are key factors in promoting brain function, you can also use nootropic supplements to further support cognitive enhancement. These supplements are designed to provide the brain with specific nutrients that can enhance its functions.

Currently, one of the most popular choices in the world of nootropics is NooCube. It claims to check all the boxes needed to qualify as a top-tier brain booster. I decided to find out if this supplement is another marketing trick or a genuine solution for improving brain health and cognitive performance.

So, I examined NooCube thoroughly, and in this review, I’ll share everything I learned about it, including its ingredients and pros and cons.

What Is NooCube?

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Our rating:
  • Improves mental energy, focus, and memory
  • Natural ingredients
  • Clinically supported
  • GMO, soy, and grain-free
Visit NooCube
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    Contains natural ingredients
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    Halts neurodegenerative disorders
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    Enhanced mental clarity and concentration
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    Heightened cognitive awareness and memory
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    Improved reaction
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    Limited availability (strictly limited to the company website)
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    Takes a while to feel the effects
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    Not suitable for everybody

As I’ve mentioned already, NooCube is one of the most popular nootropic supplements out there, made of all-natural ingredients. It comes in the form of capsules and aims to enhance brain function, increase mental energy, boost memory, and maintain your overall brain health.

Additionally, the company also claims that it reduces mental stress levels, improves mood, increases processing speed, enhances attention span, and prevents mental health issues.

When I looked at the composition of this supplement, I found that it’s a combination of herbal extracts, vitamins, and minerals. I can say from my professional experience that some of these ingredients have been clinically studied for their beneficial properties for brain health.

For example, it contains choline, which can increase acetylcholine levels in your brain, which can support cognitive functions and promote brain health.

⭐ Rating


🧪 Key ingredients

Bacopa monnieri, L-tyrosine, cat’s claw, oat straw extract

👍 Best for

Enhancing focus, cognitive functions, mental health

❌Not suitable for

People under the age of 18, pregnant or nursing mothers

🍎 Dosage form

2 capsules a day


From $64.99

Does NooCube Really Work?

In my opinion, NooCube seems like a powerful supplement because of its rich composition. The ingredients it contains can help you with cognitive enhancement, and there’s scientific evidence to back that.

While it may be hard to buy into the fact that you can boost brain function using supplements, it’s actually possible. I’ll use a simple approach to explaining how this works.

Just like any other part of our body, our brains need specific nutrients to function at their best. But many of us don’t get these nutrients through our diet, which can hold back our brain from performing at its maximum potential.

When you start taking nootropic supplements, they fill in these gaps by giving your brain the nutrients it needs to work better. So, these supplements can really improve your cognitive function and overall mental health. But it still depends on their composition and your unique needs.

However, it is important to remember that it cannot magically make you smarter overnight. It’ll take time, and you’ll also need to focus on following a healthy lifestyle.

Additionally, I have to mention that nootropics don’t work the same way for everyone, as every brain is unique. So, what works well for someone you know might not have the exact same effect on you.

How Long Does NooCube Take to Work?

According to NooCube’s official website, some users of this supplement can start experiencing positive results within the first few days of using it regularly. However, the website also states that the duration can vary from person to person, and you should take NooCube for at least 3 to 6 months.

I agree with that, as there are several factors, such as age, genes, and habits, that can influence how quickly you’ll see the effects of a nootropic supplement. So, make sure that you stay patient and consistent and also stick to the recommended dosage, which is two capsules a day with water.

I would also recommend you eat a nutritious diet and workout regularly while using NooCube or any other type of nootropics. Additionally, you can also use mental health apps to find detailed information on how to improve your overall mental well-being.

NooCube Key Ingredients

NooCube Key Ingredients
Health Reporter image

NooCube has a long list of ingredients, 12 in total, and here, I’ll help you understand a little more about them.

 #1 Choline from vita-choline

Choline is a member of the B-vitamin complex, and it’s an essential nutrient for several bodily functions. As I’ve mentioned above, it can increase acetylcholine levels in your body, which is an important neurotransmitter to perform several brain functions such as motivation, memory, and attention.

Additionally, choline can also stimulate vagus nerve activity, which can reduce brain inflammation and enhance cognitive function and mental well-being.

I should also mention that the choline used in NooCube is obtained from vita-choline (a natural source). I really liked the inclusion of this ingredient because it’s essential for the human body, and around 90% of Americans don’t meet its daily recommended dosage.

#2 Cat’s claw

Cat’s claw (Uncaria tomentosa) is a woody vine that grows in the tropical rainforests of South and Central America. NooCube comes with a concentrated 4:1 cat’s claw extract.

It’s a powerful brain nutrient, and research shows that it can decrease brain plaques and tangles. Additionally, it can also protect the brain from age-related damage and improve symptoms in people with Alzheimer’s disease.

Other than benefitting your brain, Uncaria tomentosa can also offer other advantages, such as treating arthritis, allergies, and asthma. That’s because it has anti-inflammatory and antioxidant properties and can also act as an immune booster.

#3 Panax ginseng concentrate

Panax ginseng has been used in traditional Asian medicine for centuries because of its antioxidant and anti-inflammatory effects. It also acts as a stress reliever and can reduce the symptoms of stress-related depression.

But in my opinion, the most important benefit of this ingredient for your brain is that it can improve your working memory and make you feel calmer by stabilizing your mood.

#4 Bacopa monnieri

Bacopa monnieri is a plant used for centuries in Ayurvedic medicine to support cognitive function. Also known as Brahmi, this herb is traditionally taken as a brain tonic to help boost memory, concentration, and mental clarity.

Traditional beliefs and superstitions aside, I can tell you that modern research also speaks for the benefits of this ingredient for brain health. It possesses cognitive enhancing effects, one of which improves working memory and cognitive processing speed in healthy adults.

It does this by suppressing acetylcholinesterase (AChE) activities enhancing cholinergic function. This, in turn, improves cognitive performance. Other studies have shown that bacopa monnieri can also reduce stress and anxiety, both of which can impact cognitive function.

#5 Resveratrol

Resveratrol is a type of polyphenol, a class of phytonutrients with antioxidant properties. It is found in the skin of red grapes and other fruits and vegetables, such as raspberries, mulberries, and blueberries.

Scientific research shows that resveratrol has several health benefits, including reducing inflammation, protecting against heart disease and stroke, and even slowing the aging process. In addition, it can also boost the immune system and help fight cancer.

However, I must mention that there is still a need for more clinical trials to quantify resveratrol’s impact on overall physical and mental health.

#6 Pterostilbene

Just like resveratrol, pterostilbene is a powerful antioxidant that can be found in certain berries, including blueberries, grapes, and cranberries.

It offers a wide range of benefits, such as reducing inflammation, lowering blood sugar levels, enhancing the brain’s neurotrophic factors, improving learning and memory, and decreasing cognitive decline.

However, most studies explaining the mental health benefits of this ingredient are done on animals. So, I would say that further research involving human trials is still needed.

#7 Lutemax

Another important ingredient that NooCube contains is Lutemax, which is a food supplement. Research shows that it can improve learning abilities, focus, and overall brain health. It also contains lutein and zeaxanthin, two nutrients essential for eye health.

Lutein is a carotenoid pigment found in high concentrations in the macula, the central area of the retina, whereas zeaxanthin is another carotenoid pigment that is located in the macula as well as in the lens of the eye.

Both lutein and zeaxanthin are powerful antioxidants, and they help protect the eyes from damage caused by ultraviolet light.

Another important compound that Lutemax contains is L-carnitine. It’s an amino acid that helps transport fatty acids into the mitochondria.

Lutemax also contains L-carnitine, an amino acid that helps transport fatty acids into the mitochondria. L-carnitine has been shown to improve mitochondrial function and reduce the risk of age-related vision problems.

In my opinion, this ingredient can be very beneficial for older adults and people with eyesight problems.

#8 L-tyrosine

L-tyrosine is an amino acid that plays a vital role in producing protein and nerve function, and NooCube contains 250mg of this ingredient.

According to research, poor sleeping habits and negative environmental factors can affect the levels of certain neurotransmitters, such as dopamine and norepinephrine.

These neurotransmitters are responsible for mood, focus, and energy levels while inducing self-control in ADHD patients and lowering anxiety, stress, and depression levels. 

L-tyrosine intake can increase the production of these neurotransmitters, allowing the body to continue optimal cognitive functions, as well as improve reaction time during times of stress.

A study affirms that L-tyrosine has a high potential as a treatment for ADHD due to its ability to increase serotonin and dopamine levels. That’s why many nootropics for ADHD contain this ingredient.

#9 L-theanine

NooCube contains 100mg of L-theanine, which is an amino acid commonly found in green tea and certain mushrooms. This water-soluble compound is best known for its calming and relaxing effects, and it can also improve your sleep quality

But what I find most appealing about this ingredient in the context of a nootropic supplement is that it can help with focus and attention. Additionally, it can also inhibit the release of stress hormones and can help reduce anxiety and promote relaxation.

#10 Vitamin B1

Vitamin B1, also known as thiamine, is a water-soluble vitamin that is involved in a variety of cellular processes. It helps convert glucose into energy, supports nerve function, and aids in the formation of red blood cells.

One of the biggest benefits of vitamin B1 for the brain is that it increases brain glucose utilization. If the level of this vitamin decreases in your brain, then it’ll lead to impairment of cognitive and reflex function, loss of consciousness, seizures, and even permanent/irreversible brain damage.

#11 D-biotin

Vitamin B7 (biotin) is a water-soluble compound that is a part of the B complex family. In my professional experience, I’ve seen people with biotin deficiency suffering from disrupted learning and memory functions.

I liked the fact that NooCube uses D-biotin, which is plant-based, instead of normal biotin derived from animal products, as it’s more bioactive.

#12 Vitamin B12

Vitamin B12 is present in 2.7 micrograms in NooCube. According to the recommended dietary allowance (RDA), adults need to consume 2.4 micrograms of vitamin B12 daily.

While vitamin B12 deficiency is not very common, many people still fail to consume its daily recommended amount. It can be harmful to your brain as this compound is used in many important processes in the body.

For example, it prevents damage to neurotransmitters, improves energy levels, and boosts mood. It is also a critical factor in DNA synthesis, red blood cell formation, and neurological function.

My only concern regarding vitamin B12 in NooCube is that the supplement provides slightly more than the recommended daily allowance (RDA). Although it’s not excessively high, it can be problematic if you’re also obtaining vitamin B12 from other dietary sources.

This is important because an excessive intake of vitamin B12 can lead to unwanted side effects like diarrhea, abdominal cramping, and bloating.

A Word From an MD

Expert image border HR_author_photo_Rosmy
Rosmy Barrios, MD
Medical advisor for Health Reporter

NooCube comes with all-natural ingredients, such as choline, cat’s claw, and Panax ginseng, that individually offer several benefits for your brain health. However, the number of ingredients can be a problem, as it can lead to several complications.

For example, if a supplement causes a side effect, which is possible, then it’ll be extremely difficult to pinpoint the ingredient that is the culprit. Additionally, if you’re already taking medicine, a supplement with a high number of ingredients will be more likely to interact with your existing treatment.

Lastly, it’ll also be challenging to manage the daily recommended allowances of all the ingredients present in the supplement. While NooCube might be safe for most people as it has no clinically proven side effects, it is best to tread cautiously.

You should speak with a qualified healthcare provider before taking NooCube to confirm if it’s suitable for you. It is especially true if you are on any medications for mental health (or any prescription drugs).

NooCube Benefits

The manufacturer of NooCube claims a plethora of benefits that the supplement offers. Let me explain the ones that are actually backed by scientific research.

NooCube Benefits
Health Reporter image

#1 Enhanced cognitive function

The combination of choline from vita-choline, Bacopa monnieri, and L-theanine in NooCube can enhance your cognitive function and improve mental clarity.

Choline supports neurotransmitter production, and Bacopa monnieri contributes to improved cognitive processing speed, whereas L-theanine, derived from green tea and mushrooms, aids in maintaining a calm and focused mental state.

#2 Enhanced learning abilities

The presence of L-tyrosine and cat’s claw in NooCube can offer the advantage of enhanced learning abilities. L-tyrosine boosts the production of neurotransmitters associated with mood and focus, contributing to improved learning retention.

Cat’s claw, with its brain-protective properties, assists in creating an optimal environment for absorbing and retaining new information. I think students and academics will find this benefit most useful.

#3 Boosted memory

NooCube can also be beneficial for improving your memory because of resveratrol and Bacopa monnieri. Resveratrol possesses antioxidant properties, and it can contribute to overall brain health, which is essential for memory function.

Bacopa monnieri, on the other hand, enhances memory formation and retention, making it easier to recall information when needed.

Here, I should mention that Bacopa monnieri can lead to side effects in some individuals, such as abdominal cramps, nausea, and increased stool frequency. If you experience any of these issues, make sure that you stop taking the supplement and talk to your healthcare provider.

#4 Improved sleep quality and relaxation

The inclusion of L-theanine in NooCube can contribute to improved sleep quality and relaxation. This ingredient has calming effects, and it can promote a restful sleep cycle, ensuring a rejuvenated mind upon waking. It can help you create a balanced mental state conducive to quality sleep and relaxation.

While I was researching, I found that one capsule of NooCube contains 100mg of L-theanine, and you need to take two capsules per day. It means that you’ll be consuming 200mg of L-theanine every day, which is the recommended daily intake.

In my opinion, it can be a bit of a problem if you like tea and drink it daily. That’s because it contains L-theanine and can increase your daily intake, which can cause nausea and upset stomach.

#5 Can maintain overall brain health

NooCube’s formula includes Panax ginseng concentrate and L-tyrosine, both of which can aid in reducing stress and maintaining overall brain health. The first ingredient acts as a stress reliever, minimizing the impact of stress-related depression.

The latter supports optimal cognitive function during times of stress, contributing to overall mental resilience and brain health.

NooCube Cons and Side Effects

Just like most supplements, NooCube also has its own set of drawbacks that you should know before you decide to use it. Let me explain these cons in detail.

#1 Contains gelatin (not vegan-friendly)

As I’ve discussed earlier, NooCube comes in the form of capsules, which are made of gelatin. It’s a food ingredient that’s derived from animal sources. This makes the product unsuitable for individuals following a vegan or vegetarian lifestyle.

#2 Potential side effects

While NooCube is generally considered safe, there are a few potential side effects that can take place. And I think you should be aware of them.

  • Headaches: Some users may suffer from mild headaches as a side effect of using NooCube. These headaches are typically transient and may occur as the body adjusts to the supplement’s ingredients.
  • Stomach aches: In some cases, users can experience stomach discomfort or mild gastrointestinal disturbances after taking NooCube. These symptoms are also usually temporary and may subside as the body becomes accustomed to the supplement.
  • Nausea: It’s another potential side effect of NooCube, and it’s more likely to occur if the supplement is taken on an empty stomach. However, it can also take place if the user is sensitive to a certain ingredient in the product.

I advise you to stop taking the supplement and seek medical attention immediately if you experience any side effects, whether or not it’s mentioned here.

#3 High price tag

Honestly, NooCube is an expensive supplement, as a single-day dose costs you $2.16. It’s not something that everyone can afford easily. So, I would say that it can be a dealbreaker for individuals who are seeking a more budget-friendly option.

What Do Online Reviews Say About NooCube?

While examining and testing a product, I always read its online reviews. They provide me with valuable insights into the firsthand experiences of other individuals and help me build my expectations realistically.

Here are some real-world reviews explaining NooCube results.

Screenshot from
Screenshot from

I agree with Mark’s views, as the product sold on Amazon is not the same as the one available on the official website. I’ve also seen some other reviews on Amazon as well stating the same thing. So, it’s best to buy this supplement from their official website.

Felt like a relief
Screenshot from
Felt like a relief
Screenshot from

Stacy also found NooCube to be a useful supplement. Although she didn’t experience any results quickly, she stayed consistent, and the product brought a positive change. The same can happen with everyone, as supplements act differently for different individuals.

Helped me focus all day at work - desktop
Screenshot from
Helped me focus all day at work
Screenshot from

Jeffrey also shares the same thoughts about NooCube, as it worked for them as well. But the most important point in this review is that the user tried multiple brain supplements, and none of them worked for them. So, it can also be the case with NooCube.

How Much Does NooCube Cost?

NooCube is pretty costly, but there are three different options available to choose from:

  • 1-Month supply: $64.99 (1 jar with 60 capsules)
  • 3-Month supply: $129.99 (3 jars with 180 capsules)
  • 5-Month supply: $194.99 (5 jars with 300 capsules)

The second and third options cost less than the first one, which is good. However, I must mention that if you haven’t used this supplement before, it might not be smart to go for the bigger packages. That’s because you don’t know how your body will react to it.

So, it’s a better idea to start with a smaller package to see how it works for you before buying more. This way, you can decide if it’s right for you without spending too much money upfront.

NooCube vs. Alternatives

NooCube is undoubtedly popular in the world of nootropic supplements, but it’s not the only option available in the market. There are many other reputable brands out there that you can consider, and I’ve selected the best ones for you.

Comparison Winner: NooCube
Mind Lab Pro
Alpha Brain
Performance Lab Mind
Qualia Mind
Hunter Focus

13 science-backed ingredients

No prescriptions required


Discount on bulk purchase of 3–5 bottles

60-day money-back guarantee

Free shipping

Research-backed ingredients


No additives

100% satisfaction guarantee

Natural and safe formula

Gluten-free and non-GMO

30-day money-back guarantee

Clinically proven ingredients

100% natural

Natural ingredients

Stimulant free

Free shipping on purchases above $180

10% discount for email subscriptions

Additive and filler-free

30-day money-back guarantee

Bulk buy discounts

7 scientifically-backed ingredients

Optimal ingredient doses

Made in an FDA-certified facility

Easy-to-swallow capsules

100% natural

Free of dairy, gluten, and stimulants

15% discount for military, first responders, and medical providers

10% OFF on email subscriptions


1–2 pills a day is enough to reap benefits

All-natural ingredients

30-day money-back guarantee

Filler and additive-free

Soy-free, non-GMO

Well researched

Discount on first subscription delivery

100-day money-back guarantee

Non-stimulant option available

6 formulas with different effects

Available with or without stimulants

Offers wellness coaching

Good customer support

Free shipping

30-days money-back guarantee

Free delivery

Offers a 10% discount on email subscriptions

Science-backed ingredients

Gluten, soy, and additive-free

30-day money-back guarantee


Purchase is only from the official website

Not available over the counter at retail stores

Can cause minimal side effects

Purchase is only through the official website

Insufficient amounts of some ingredients

May cause mild side effects

Not suitable for people under 18

Not suitable for those sensitive to stimulants

Only available in the US

Individual results may vary

Not safe for breastfeeding and pregnant women

Purchase is only from the official website

Not suitable for pregnant or breastfeeding women

Lack of transparency about ingredient doses

Unproven claims

Some ingredients are not recognized for their claimed effects

Under dosed ingredients

Purchase is only from the official website

Lacks some essential antioxidants and vitamins

Some ingredients are underdosed

Other ingredients lack clinical backing

You have to take 7 capsules daily for a full dose

Has caffeine content and can disrupt sleep

Some ingredients are not science-backed

Not vegetarian or vegan-friendly


Is NooCube safe?

NooCube is generally considered safe for most individuals. However, there are a few side effects, such as nausea and headaches, that some people can experience, especially during the initial period of use. These side effects occur as your body gets accustomed to the product.

How to take NooCube?

According to the official website, users are recommended to take two capsules every day, with or without food.

Where can I buy NooCube?

You can only get the supplement on the official website. The manufacturers also provide a 60-day money-back guarantee upon any purchase made on the website.

Are nootropics legal to use?

Yes, most nootropics are legal to use globally.

How I Tested

I follow a systematic approach to evaluate a product, and it covers four important factors, including quality, effectiveness, price, and brand reputation. Read on to learn more about these factors regarding NooCube.

Quality 9/10

Employing a dietary supplement to aid cognitive enhancement is no minor issue by any metric. As such, the quality of ingredients must be top-tier to ensure safety. 

NooCube is undeniably a high-quality supplement made of all-natural ingredients, and it’s manufactured in an FDA-registered facility. Additionally, the manufacturer of the supplement also claims to have tested the ingredients and deemed them safe enough to make a consumable product.

Effectiveness 7/10

NooCube can take a few weeks or even several months to bring positive changes, but at the same time, it can also cause some side effects. Additionally, it’s important to note that nootropics are a relatively new category of supplement, and not much is known about their efficacy.

Their results can vary from person to person, and it’s possible not to experience any positive change at all. So, this is something you should keep in mind.

Price 6/10

NooCube might be cheaper than some other nootropic supplements, but it’s still pretty expensive. While you can save some bucks by going with a 3-month or 5-month supply, you’ll need to opt for the 1-month supply option to test out the product. And frankly speaking, it’s not a very budget-friendly option.

Brand reputation 9/10

NooCube is manufactured by Wolfson Brands, a UK company that happens to be a well-known name in the health and fitness market. While it’s a bit unclear where in the world NooCube is manufactured, Wolfson Brands states that NooCube is made in FDA-approved facilities. 

NooCube: The Final Verdict

NooCube features a rich formula that contains all-natural ingredients. Each ingredient that the supplement contains is scientifically proven to help you improve your brain health. It can enhance your focus, productivity, and memory and maintain your overall mental well-being.

But it’s also important to note that taking brain enhancers alone will not necessarily yield the level of results you desire. For that, you need to eat healthily, exercise, practice stress management, and get enough sleep.

Lastly, if you’re concerned about NooCube or have used it but didn’t experience any positive results, you can consider looking at other options available in the market.

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Written by Edibel Quintero, RD
Fact checked by Rosmy Barrios, MD
Last update: October 10, 2023
17 min read 1323 Views 0 Reviews
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