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Home arrow Health arrow Gut Health arrow Gut Connect 365 Review: Is It Really Helpful for Gut Health?

Gut Connect 365 Review: Is It Really Helpful for Gut Health?

Written by Edibel Quintero, RD
Fact checked by Rosmy Barrios, MD
Last update: September 21, 2023
12 min read 1759 Views 3 Reviews
clock 12 eye 1759 comments 3

Gut Connect 365 is a powdered supplement that claims to support your digestive system. I examined this supplement thoroughly to find out if it actually works.

Gut Connect 365 Review

How do we vet brands and products? Learn more.

A properly functioning gut isn’t only essential for efficient digestion, it also plays a critical role in maintaining your overall health. It helps you strengthen your immune system, balance moods, and improve energy levels.

Using a dietary supplement is a common way to encourage a healthy gut lining and support digestive health. Gut Connect 365 is a popular option, which is designed to nourish, strengthen, and protect your gut.

The creators of this product strongly believe that it can reduce fatigue associated with constipation, which can also lead to improved sleep and better weight management. These are astonishing claims, and as a medical professional, I wanted to make sure they’re actually true.

So, I decided to examine Gut Connect 365 thoroughly, and in this review, I’ll share everything I’ve found about this product, including its pros and cons.

What Is Gut Connect 365?

gut connect 365 logo
Our rating:
  • Comes in two flavors
  • Easy to use
Learn More
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    Scientifically proven natural ingredients
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    Could help with leaky gut syndrome symptoms
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    May give you higher energy levels
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    Can help you sleep better during the night
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    Very expensive for each jar of supplement
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    You can only buy the product on their website
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    Ingredients might interact with certain medications
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    Aloe vera extract could be toxic for some people
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    No evidence that ingredients actually support gut health
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    Potential side effects for high-risk groups

Gut Connect 365 is a formulated, powdered supplement that contains a blended mixture of 9 superfoods. It’s said that these natural ingredients work to improve gut health, especially in those who deal with recurring bouts of constipation. This dietary supplement also claims to strengthen a healthy gut lining.

One of the first things that I noticed about this formula is that it was created by a certified medical doctor, Dr. Vincent Pedre. I liked his views as he believes that the future of healthcare relies on Eastern and Western medicine. That’s why he has used 9 natural superfoods to create Gut Connect 365 for digestive treatment.

Licorice root extract and maitake mushroom extract are two of the main ingredients used in this dietary supplement. As a medical professional, I know that licorice root extract is beneficial in helping people suffering from gastrointestinal diseases.

Whereas maitake mushroom extract can stimulate the growth of beneficial bacteria in your gut, called probiotics. It means that it can indirectly work as a colon cleanser to help your body get rid of waste materials and toxins.

At the time of writing, Gut Connect 365 is available in two different flavors, including vanilla cinnamon and chocolate coconut. You can buy a single or a bundle of 3 or 6 jars of this powdered supplement, each of them being 7.8oz.

⭐ Rating


✅ Pros

Natural ingredients, might help with a leaky gut syndrome

❌ Cons

High price, insufficient clinical research

🍎 Dosage form


🔔 Key ingredients

L-glutamine, MCT oil powder, slippery elm bark

💰 Price

From $54

How to Use Gut Connect 365?

The recommended dosage for Gut Connect 365 is 1 scoop in 8oz of water per day. At this rate, a 7.8oz jar should last you around one month.

All you need to do is stir the powder in water and drink it before or after a meal. Just make sure not to go over the daily dosage, as it may cause some unpleasant side effects, such as bloating.

It’s important to bear in mind that Gut Connect 365 does contain aloe vera. This ingredient might have carcinogenic effects and can even be toxic.

So, my advice is to consult your doctor before taking this dietary supplement, especially if you have gut health issues like irritable bowel syndrome or inflammatory bowel disease.

How Long Does It Take for Gut Connect 365 to Work?

Everyone is unique, so the time that Gut Connect 365 takes to work can vary from person to person. But generally, you can expect to start experiencing results after taking this supplement regularly for up to two weeks. It means you’ll need to be patient and consistent to let all the natural ingredients of the product improve your gut health.

Another important point to note here is that the supplement might work differently for everyone, depending on their individual digestive health. For example, if you have existing gastrointestinal symptoms, you might not feel comfortable taking a dietary supplement.

I should also mention that the creator of Gut Connect 365, Dr. Vincent Pedre, claims that it’s effective in soothing leaky gut syndrome. However, there’s no scientific evidence (at least currently) to suggest that this product can improve gut lining, beat bloating, or support weight loss.

Key Ingredients of Gut Connect 365

According to its creators, Gut Connect 365 is designed to strengthen and protect your gut lining. However, it’s important to note that its ingredient statements haven’t been evaluated by the Food and Drug Administration.

Let’s take a look at the few key ingredients that the Gut Connect 365 supplement contains.

Key Ingredients of Gut Connect 365

#1 L-glutamine

L-glutamine is an amino acid that’s essential to maintain muscle protein. But according to research, supplements containing this amino acid can also help with constipation and benefit the digestive system overall.

However, L-glutamine deficiency in the human body is very rare, so you don’t need a supplement for that. But if you are under constant stress from illness or recovering from an injury, you might need to increase your L-glutamine intake.

#2 Slippery elm bark

Slippery elm is a tree native to Eastern North America, and it’s known for its health benefits for the human body. The bark of this tree is demulcent, which means it can soothe the lining of the intestines, and it’s also believed to reduce intestines and stomach irritation.

One study found that slippery elm bark may enhance bowel function. It also can help treat acid reflux and reduce inflammation and irritation.

#3 Organic Marshmallow Root

This perennial herb is used to protect the digestive tract lining, and it’s believed to treat constipation and diarrhea. That’s why it’s commonly used in the production of several types of supplements.

However, there are almost no studies to back the health benefits of this root. At this time, we only have animal studies, and that’s not enough to say that it works for humans as well.

But what I can tell you about this herb is that it can interact with diabetes and lithium drugs. Additionally, it can also affect the absorption of any type of medication by coating your stomach.

Therefore, I recommend you avoid using this supplement (or any other one containing marshmallow root products) if you’re on medication.

#4 Aloe vera

While it works as a great natural remedy when the skin is irritated, burned, or very dry, using aloe vera internally can lead to unpleasant side effects.

If you consume it in high amounts, it can lead to stomach cramps and pain, muscle weakness, and even heart disturbances.

In addition, it’s even believed to be a potential carcinogen when used internally. In rare cases, using aloe vera might even cause kidney failure. So, be extra careful.

#5 Quercetin Dihydrate

Another important ingredient in Gut Connect 365 is quercetin dihydrate, which is believed to have anti-inflammatory properties. It’s a natural plant-derived compound, known as a flavonoid, and it can reduce the inflammation in your body that leads to a leaky gut.

Research shows that quercetin dihydrate can also regulate the gut microbiota composition and prevent harmful substances from leaking into our body.

Expert’s Comment

Expert image border HR_author_photo_Rosmy
Rosmy Barrios, MD
Medical advisor for Health Reporter

The Gut Connect 365 supplement is designed to strengthen and protect your intestinal lining. It’s also said that consuming this powdered supplement can reduce your digestive issues and increase your energy levels.

Some of the ingredients it contains, such as licorice root extract and maitake mushroom extract, can be beneficial for your digestive health. But other ingredients like organic marshmallow root and aloe vera can affect your health negatively if you’re not careful.

Organic marshmallow root can interact with medication, while excessive aloe vera consumption can lead to stomach discomfort. Therefore, it’s critically important to be extra careful while using Gut Connect 365 or any other supplement.

Make sure that you consult with your healthcare provider before starting to use any supplement. They’ll provide you with expert advice depending on your medical history.

Benefits of Gut Connect 365

Now, let me explain the potential health benefits of Gut Connect 365 based on the ingredients it contains.

#1 Relief from constipation

As mentioned already, maitake mushroom extract and L-glutamine are two of the main ingredients in Gut Connect 365. The first one can help you get rid of waste from your body efficiently for increased comfort. At the same time, the latter can promote regular bowel movements and relieve constipation.

#2 Strengthening the gut lining

Gut Connect 365 claims to strengthen and protect the gut lining. It contains slippery elm bark, which is demulcent and can soothe and protect the digestive tract lining, but we need more science-based studies to be sure.

#3 Improved digestive health

As I’ve discussed above, licorice root extract can be beneficial for people experiencing gastrointestinal diseases. Additionally, maitake mushroom extract can stimulate the growth of probiotics in your gut. Both these benefits of Gut Connect 365 can help you improve your overall gut health.

#4 Balancing mood

A growing body of research suggests that there is a link between gut health and mental well-being. It means that stomach-related problems can lead to mental issues, such as anxiety, and vice versa. If your gut health is up to the mark, it can positively impact your mood by reducing feelings of distress and discomfort.

Cons and Side Effects of Gut Connect 365

Just like any other supplement, Gut Connect 365 also has its own set of downsides. Let’s discuss them in detail because it’s important to know the potential cons and side effects of a supplement before using it.

#1 Temporary digestive discomfort

Some individuals may experience an initial adjustment period when starting Gut Connect 365. It happens when your body is not used to consuming certain types of nutrients in high amounts. It can lead to temporary discomfort like increased gas, bloating, or constipation.

#2 Dehydration

The supplement’s ingredients can also cause the gut to absorb more water, which can lead to a feeling of dehydration in some people. Therefore, I would recommend you increase your water intake if you’re planning to use this supplement.

#3 Aggravation of leaky gut symptoms

It’s possible that people with leaky gut syndrome find their symptoms worsen after taking Gut Connect 365. Chronic diarrhea, headaches, fatigue, joint pain, skin problems, and difficulty concentrating are possible signs of this condition.

If you have a leaky gut and experience worsening symptoms, you must stop taking the supplement and seek medical care as soon as possible.

#4 Interaction with medication

Gut Connect 365 contains organic marshmallow roots, which can interact with certain medications, such as lithium and diabetes drugs. It can also reduce the effects of medicines you’re taking.

So ideally, you should avoid this product, regardless of the type of medication you’re following.

#5 Limited scientific evidence

While Gut Connect 365 claims to offer various gut health benefits, there’s limited scientific evidence to support its specific effectiveness and safety. More research is needed to validate its claims and potential side effects.

#6 High price tag

Gut Connect 365 is not a very affordable product. In fact, its price tag is higher than most supplements of the same class. I think it can be a deal breaker for people who are on a tight budget.

What Do Online Reviews Say About Gut Connect 365?

Other than examining and testing products myself, I also read online reviews. This allows me to figure out what other people have to say about a product and what to expect.

I did the same with Gut Connect 365, and here’s what I found.

What Do Online Reviews Say About Gut Connect 365

I’m happy for Jesus Salas that they’re satisfied with Gut Connect 365. I also agree with their other comment about the product’s price, as it’s pretty expensive.

However, I don’t know what this user means when they say that they “bought it directly from the manufacturer.” That’s because the manufacturer of Gut Connect 365 is United Naturals, and the price on the official website is similar to other stores.

What Do Online Reviews Say About Gut Connect 365

Again, I’m glad that this user found Gut Connect 365 useful. But as they’ve mentioned, the supplement might not work for everyone because of its formulation. It contains so many ingredients, and not all of them are disclosed in the Amazon listing.

What Do Online Reviews Say About Gut Connect 365

Sadly, Alma is one of those users who did not experience any health benefits from using Gut Connect 365.

How Much Does Gut Connect 365 Cost?

As discussed in the “reviews” section, Gut Connect 365 is not a cheap product, as a single jar of 7.8oz costs $54. It’s almost double the price of other supplements that offer better performance to deal with stomach issues.

If budget is an important concern for you, it would be wise to explore alternative options before making your final decision.

Gut Connect 365 vs. Alternatives

While Gut Connect 365 might be beneficial for your gut health, it’s not the only option available in the market.

Comparison Winner: ColonBroom
Garden of Life Raw Organic Fiber
Gut Connect 365
Humann SuperBeets

Completely organic and has no sugar

You can feel bowel movement in the first 24–72 hours after consumption 

Free delivery in the U.S. 

Boosts your energy and helps prevent disruptive sleep 

Psyllium husk (natural fiber) is a gentle, bulk-forming laxative for your gut

Supports muscle growth

Non-GMO and gluten-free supplement

Contains fiber from nutritious organic superfoods

Suppresses hunger cravings

Helps with constipation

Restores good gut bacteria

Research-backed ingredients that encourage a healthy digestive system

60-day money-back guarantee for all customers 

Gluten-free product, which benefits those with celiac disease

Lowers blood pressure

Adds nutrients to your diet

Encourages healthy blood circulation

Boosts stamina

Supports heart and gut health

Promotes the growth of good gut bacteria


Only one flavor to choose from 

You will have to increase your daily water intake 

Potential side effects for those who have a sensitive stomach 

Chalky powder

High-calorie supplement

Only one sizing option available

Limited flavors

Pricing is very expensive for a product that only lasts one month

You can’t buy the powder elsewhere 

Ingredients haven’t been proved to strengthen your gut and digestive system

Aloe vera extract could cause gastrointestinal side effects in people

Limited flavors

Not suitable for people with low blood pressure

Reports of powdery chunks


Let’s take a look at some frequently asked questions about Gut Connect 365:

Where to buy Gut Connect 365?

You can buy this powdered supplement from Amazon or other online retailers.

Is Gut Connect 365 a laxative?

No, it’s not a laxative, but it is said to help encourage bowel movements.

Does Gut Connect 365 work for weight loss?

This powder supplement won’t progress weight loss, but it may help those who are eating healthy.

What are the flavors of Gut Connect 365?

There were two flavors at the time of writing this article: chocolate coconut and vanilla cinnamon.

How I Tested

Here’s the systematic approach that I use to test every new product, and I followed the same for Gut Connect 365. It’ll provide you with valuable insights into the quality, effectiveness, price, and brand reputation of this supplement.

Quality 7/10

While the representation and manufacturing quality of Gut Connect 365 is top-notch, I can’t say the same about the quality of its ingredients. That’s because they haven’t been evaluated by the FDA.

It’s important to note that the information about the ingredients of Gut Connect 365 is available on the official United Naturals website (and some others), but it’s not listed on Amazon.

In my opinion, it’s not a wise move because Amazon is one of the main online retailers that people use. Therefore, all the details about the product should be mentioned there so that people can easily find out what they’re buying.

Effectiveness 7/10

Some of the ingredients used in Gut Connect 365 can be beneficial for your gut health, but others can be counterproductive. Plus, there’s no scientific evidence to support that this supplement can help with leaky gut syndrome symptoms.

Price 7/10

Gut Connect 365 is very expensive compared to other supplements. If you decide to get the $244 package (with 6 jars), you would be spending $488 a year just to get 12 months’ worth of product. This pricing might not suit everyone wanting to try a new supplement.

Brand reputation 9/10

Dr. Vincent Pedre seems very passionate about making the right products for people. He is dedicated to using ingredients that support your health and well-being, and I respect that. People may feel more inclined to buy supplements from a certified medical professional.

Gut Connect 365: The Final Verdict

While Gut Connect 365 holds promise in supporting gut health, increasing energy levels, and improving sleep quality, its effectiveness can vary among individuals.

It’s formulated by a certified medical professional, Dr. Vincent Pedre, who truly believes that it’s great for your overall well-being. However, you should only incorporate it into your life after consulting with your healthcare provider.

Lastly, if you have issues related to your gut, you can try specially-designed fiber supplements to improve your symptoms.

Was this article helpful?
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Written by Edibel Quintero, RD
Fact checked by Rosmy Barrios, MD
Last update: September 21, 2023
12 min read 1759 Views 3 Reviews
3 Reviews
  1. user
    Sidney Exp.
    21 Jul, 2023 at 9:11 am
    7/10 Less constipated since drinking this

    I’m less constipated since drinking this. but colonbroom is better in my opinion and waaay cheaper

    reply reply reply
  2. user
    25 Jul, 2023 at 6:11 pm
    8/10 I liked it

    I liked it, vanilla cinnamon taste is great

    reply reply reply
  3. user
    Tina Lee
    27 Jul, 2023 at 3:12 pm
    9/10 worth the money

    It’s worth the money, as it reduced my bloated belly. I can wear tight pants again!!

    reply reply reply

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