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Home arrow Health arrow Mental Health arrow 7 Best Nootropics for Sleep: Say Goodbye to Sleepless Nights in 2024

7 Best Nootropics for Sleep: Say Goodbye to Sleepless Nights in 2024

Dr. Donika Vata
Written by Donika Vata, MD
HR_author_photo_Edna
Fact checked by Edna Skopljak, MD
Last update: January 3, 2024
9 min read 1012 Views 0 Reviews
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Nootropics are natural supplements that enhance mental function and clarity by boosting concentration, energy, and cognitive abilities. But which nootropics work best for sleep?

best nootropics for sleep

How do we vet brands and products? Learn more.

A good night’s sleep is essential. It improves your mood and promotes healthy bodily and mental functioning.

Some people can easily fall asleep, while others struggle severely to fall and stay asleep through the night.

Sleep deprivation can negatively affect various body parts and mental processes, including memory, learning, mood, emotions, and several biological processes.

Some nootropics may help induce sleepiness. The main purpose of these nootropic pills is to enhance cognitive abilities, including learning and memory. However, some can significantly improve the quality of your sleep.

Explore the best nootropics for sleep to find one that matches your needs.

#1 Best overall star
Noocube Logo
4.5
stars
  • Enhances the sleep cycle and boosts the melatonin production
  • Lessens stress and anxiety
  • Stimulates the mind and calms the nervous system
Visit Performance Lab
Visit Noocube
#2
mind lab pro logo
4.4
stars
  • Contains 11 natural ingredients that improve mental clarity and energy
  • Increases serotonin production
  • Promotes faster and longer sleep
Visit Performance Lab
Visit Mind Lab Pro
#3
Performance Lab Mind logo
4.3
stars
  • Calms nerves and reduces stress
  • Stimulates brain regeneration and muscle recovery
  • Improves the deep sleep state
Visit Performance Lab
Visit Performance Lab

The 7 Best Nootropics for Sleep: No More Sleepless Nights

Nootropics are gaining popularity as a way to improve sleep and overall cognitive function. With so many different types of nootropics available, knowing which ones are best for improving your sleep can be difficult. 

Discover the 7 best nootropics for sleep, their benefits, and how they can help you get a better night’s rest. 

#1 NooCube Sleep – Overall best nootropic for sleep

Noocube Logo
Our rating:
4.5
stars
  • Provides a feeling of calmness
  • Reduces oxidative stress
  • Improves melatonin production
  • Relaxes muscles
  • Improves mental clarity
  • Boosts metabolism
Visit NooCube

NooCube’s Sleep nootropic from Wolfson Brands is rated as the best nootropic for sleep. It’s a natural sleep aid designed to enhance the sleep cycle, lessen stress and anxiety, and stimulate the mind. 

NooCube Sleep Upgrade is free from GMOs and chemical additives, making it safe for daily use. The main ingredients are calcium carbonate, magnesium citrate, and lavender essential oil, which work together to induce relaxation in the body and mind.

The main goal of each ingredient in Sleep Upgrade is to reduce anxiety and stress, which are the main causes of poor or no sleep.

Magnesium interacts with GABA (gamma-aminobutyric acid) receptors. GABA is a neurotransmitter responsible for calming brain activity. By calming the nervous system, magnesium may assist in getting your body and mind ready for sleep.

Calcium carbonate is well known for promoting restful sleep. It stimulates melatonin production, a hormone that controls sleep cycles. Increasing the melatonin in your body will help you feel more sleepy and fall asleep faster.

Lavender is another ingredient in this product that has been used for centuries as an essential oil to promote hair growth and treat the skin. Surprisingly, lavender can also induce sleep. Inhaling lavender before bed has been shown to improve sleep quality by lowering blood pressure and heart rate.

Sleep Upgrade can also function as a nootropic to improve mental focus and lessen brain fog. The nutrients supporting the brain help maintain mental clarity, and the potent antioxidants shield the brain from oxidative stress.

Pros
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    All-natural formula
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    Zero stimulants
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    Science-backed ingredients
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    Vegan-friendly
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    Offers a 60-day money-back guarantee
Cons
  • checkmark
    Only available on its official website
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    Results can vary from person to person

#2 Mind Lab Pro – Best for relaxation  

mind lab pro logo
Our rating:
4.4
stars
  • Improves brain health
  • Boosts brain energy
  • Enhances relaxation
  • Boosts mood
Learn More

Mind Lab Pro is a nootropic supplement with 11 natural ingredients that focus on four distinct brain pathways. The results are better cognitive function, mental energy, and clarity.

The main ingredient in Mind Lab Pro that promotes better sleep is L-theanine, which increases alpha brain waves. Alpha brain waves are the highest frequency waves that help you stay calm and relaxed, improving sleep quality. 

Brain waves also increase serotonin production, a chemical that helps regulate mood, boost brain energy, and improve happiness. 

Serotonin then converts into melatonin in the pineal gland, which ‌promotes sound and restful sleep.

L-theanine also raises GABA levels in the brain. A combination of GABA and L-theanine has been shown to promote faster and longer sleep.

Studies also show that L-theanine can enhance sleep quality by promoting relaxation, reducing anxiety, and not acting as a sedative. L-theanine may also act as a nootropic for attention deficit hyperactivity disorder (ADHD) and help children with this condition sleep better.

Pros
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    No artificial additives
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    All-natural ingredients
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    Non-GMO
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    60-day money-back guarantee
Cons
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    Available on the official website only
  • checkmark
    Shipping charges apply

#3 Performance Lab Sleep – Best for melatonin production

Performance Lab Mind logo
Our rating:
4.3
stars
  • Regulates circadian rhythm
  • Includes a natural source of melatonin
  • Relaxes muscles
  • Calms nerves
  • Extends deep sleep phases
Learn More

Performance Lab Sleep is formulated in the UK and manufactured in the US by Opti-Nutra. It has 100% natural nutrients that work together to soothe muscles, calm nerves, and reduce the stress that disrupts sleep so that you can have the best night’s rest. 

It also stimulates muscle recovery and brain regeneration to help you feel refreshed and renewed by extending and improving the deep sleep state.

The supplement contains no allergens and offers ingredients that help you fall asleep faster and wake up rested and renewed. It combines magnesium, L-tryptophan, and Montmorency tart cherry.

Performance Lab Sleep has 3 types of magnesium: magnesium bisglycinate, magnesium taurate, and NutriGenesis magnesium.

Magnesium is widely known for its ability to relax muscles and nerves and lower blood pressure, another important factor in how the body encourages sleep onset.

Tryptophan produces serotonin, which forms the sleep-inducing hormone melatonin. 

Performance Lab Sleep also offers melatonin from Montmorency tart cherries, the most abundant natural source of melatonin. It promotes the pineal gland’s normal melatonin production and release, producing more wholesome, cozy, and peaceful sleep and increasing sleep duration.

Pros
  • checkmark
    Non-GMO
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    Vegan- and vegetarian-friendly
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    Allergen-free
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    Gluten- and soy-free
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    Offers a 30-day money-back guarantee
Cons
  • checkmark
    Purchase is only from the official website
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    Large size of capsules

#4 Magnesium Breakthrough – Best for combating stress 

bioptimizers-logo
Our rating:
4.2
stars
  • Improves immunity
  • Boosts metabolism
  • Improves blood pressure
  • Promotes relaxation
  • Improves heart health
  • Improves muscle recovery
Learn More

Manufactured by BiOptimizers, Magnesium Breakthrough is designed to fight stress and give you enough sleep. These pills enhance the body’s biochemical processes, which promote relaxation, sound sleep, an effective immune system, and many other health benefits.

Stress can cause many side effects in the body, including insomnia. And a magnesium deficiency can lead to stress and several issues, including sleeplessness, cardiovascular problems, a slower metabolism, pain, migraines, and low energy levels.

Magnesium Breakthrough releases magnesium in the body and soothes the user, reducing stress and promoting relaxation.

Magnesium helps improve brain function and addresses the underlying causes of stress. It reduces the symptoms of depression and anxiety, promoting sleep.

Magnesium Breakthrough has all 7 kinds of naturally occurring magnesium, which combats magnesium deficiency in various ways. They include magnesium chelate, magnesium citrate, magnesium bisglycinate, magnesium malate, magnesium aspartate, magnesium taurate, magnesium orotate, and rice.

Pros
  • checkmark
    One-year money-back guarantee
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    Free shipping within the US for a purchase of over 3 bottles
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    No additives or preservatives
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    Includes 7 effective types of magnesium
Cons
  • checkmark
    Purchase is only through the official website
  • checkmark
    Not for people under 18

#5 Nooceptin – Best for reducing stress and anxiety

nooceptin logo
Our rating:
4.2
stars
  • Reduce stress and anxiety
  • Boosts mood
  • Regenerates brain cells
  • Improves brain blood flow
  • Boosts REM sleep
Learn More

Nooceptin is a natural nootropic supplement designed to improve mental function, strengthen the brain, and relieve stress and anxiety.

Nooceptin has a combination of ingredients formulated to improve sleep quality. Components such as L-theanine and Rhodiola rosea extract can lower stress and anxiety levels, enhancing sleep quality.

L-theanine supplementation has been shown to improve sleep quality in children with attention-deficit hyperactivity disorder (ADHD). It can also help reduce sleep latency – the time it takes to fall asleep.

Rhodiola rosea can enhance sleep architecture and quality by boosting deep and REM sleep. It can also improve oxygen saturation, which may have therapeutic benefits for people who have sleep apnea.

Nooceptin’s special blend of natural ingredients also helps improve blood flow to the brain, which may calm the brain and prepare you for sleep. This makes Nooceptin a great option for anyone looking to get a better night’s sleep because it can help enhance both the quality and duration of sleep.

Pros
  • checkmark
    Rich, scientifically backed ingredients
  • checkmark
    Made in an FDA-inspected facility
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    Easy-to-swallow capsules
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    Good customer support
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    30-day money-back guarantee
Cons
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    Higher pricing point
  • checkmark
    Only available from the official website

#6 Alpha Brain – Best for increasing alpha brain waves

onnit logo
Our rating:
4.1
stars
  • Improves alpha brain wave activity
  • Increases neurotransmitters
  • Reduces anxiety and stress
Learn More

Alpha Brain is a nootropic supplement that can help you focus more clearly, improve your memory, and feel less stressed and anxious.

This supplement contains nootropic ingredients that have undergone clinical testing and may help increase alpha waves in the brain, decrease stress and depression, and enhance sleep quality. 

What sets Alpha Brain apart is its ability to reduce anxiety, promote relaxation, and stimulate better sleep quality.

Like the other nootropic supplements listed in this article, Alpha Brain contains L-theanine, which is necessary to produce alpha waves that improve sleep quality. 

L-tyrosine, another ingredient in Alpha Brain, is an amino acid that creates important neurochemicals that affect mood and sleep habits.

Depression affects many people’s ability to sleep well. While the exact causes of depression are unknown, one theory holds that an imbalance in neurotransmitters like serotonin and dopamine in the brain causes it.

L-tyrosine is a likely remedy for depression since it can increase the neurotransmitters in your brain.

It’s well known that regular exercise is essential for supporting healthy sleep. Tyrosine is one of the substances and supplements that may help with peak performance.

Pros
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    Refund guarantee
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    Third-party tested
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    Natural, non-irritant ingredients
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    Science-backed ingredients
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    No caffeine, dairy, gluten, or nuts
Cons
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    Limited studies available
  • checkmark
    Higher pricing point

#7 NeuroFuel – Best for melatonin production

natural stacks logo
Our rating:
3.9
stars
  • Boosts motivation and focus
  • Combats brain fog
  • Promotes the synthesis of neurotransmitters
Learn More

NeuroFuel (NF) is a nootropic supplement that promotes attention, deep concentration, mental clarity, memory consolidation and recall, and processing speed. 

NeuroFuel is designed to eliminate mental fog, improve attention, and provide constant energy. This revolutionary composition helps safeguard brain health while enhancing memory and focus.

NeuroFuel supplement contains ingredients that support brain function and sleep. There are no artificial or chemical components added that might have negative effects. Each NF element is supplied in a specific way for the dosage to achieve the desired benefits effectively.

One of the potent ingredients in this supplement that promotes sleep is vitamin B6. Vitamin B6 is a necessary nutrient for synthesizing three neurotransmitters – GABA, tryptophan, and serotonin – all of which are converted to melatonin and help promote deeper sleep, as well as combat sleep deprivation.

Deficiency in vitamin B6 has also been associated with symptoms of depression and insomnia.

Pros
  • checkmark
    Free shipping in the US
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    Offers 20% off on orders
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    100% money-back guarantee
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    Vegan-friendly
Cons
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    Some ingredients are ineffective
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    Only 15 servings per bottle

Comparison Table

Comparison Winner: NooCube
4.5
stars
4.4
stars
4.3
stars
4.2
stars
4.2
stars
4.1
stars
3.9
stars
Brand
NooCube
Mind Lab Sleep
Performance Lab Sleep
Magnesium Breakthrough
Nooceptin
Alpha Brain
Neuro Fuel
Pros

All-natural formula

Zero stimulants

Science-backed ingredients

Vegan-friendly

Offers a 60-day money-back guarantee

No artificial additives

All-natural ingredients

Non-GMO

60-day money-back guarantee

Non-GMO

Vegan- and vegetarian-friendly

Allergen-free

Gluten- and soy-free

One-year money-back guarantee

Free shipping within the US for a purchase of more than 3 bottles

No additives or preservatives

Includes 7 effective types of magnesium

Rich, scientifically backed ingredients

Made in an FDA-inspected facility

Easy-to-swallow capsules

Good customer support

30-day money-back guarantee

Refund guarantee -Third-party tested

Natural, non-irritant ingredients

Science-backed ingredients

No caffeine, dairy, gluten, or nuts

Free shipping in the US

Cons

Only available on the official website

Available on the official website only

Shipping charges apply

Purchase is only from the official website

Size of capsules

Purchase is only through the official website

Not for people under 18

Higher pricing point

Only available from the official website

Limited studies available

Higher pricing point

Some ingredients are ineffective

Only 15 servings per bottle

How to Choose the Best Nootropics for Sleep 

Since nootropics are supplements, the FDA does not regulate them. This makes it easier to get many fake, low-priced, and poorly produced options that might harm your health. Here’s how we test nootropics for sleep before recommending them to you.

Quality 

We thoroughly examined each composition, focusing on ingredients that are high-quality, natural, and based on scientific research to improve sleep. 

We check the ingredient list and research them to ensure they’re not unnecessary additives. Low-quality supplements may have additives that prevent your body from absorbing the active ingredients. 

Price 

We compare the cost of the product to ensure it’s reasonable and in line with the overall quality and efficacy of the sleep nootropic.

Brand reputation 

We ensure that the nootropic brands we recommend test their products at third-party labs to confirm their ingredients are pure and free of biological contaminants or other potentially dangerous components.

Additionally, the business should have experienced nutritionists and outstanding customer service. 

Effectiveness

We check that the nootropics’ nutrition labels are as advertised. A supplement may claim to contain a specific nootropic, but this does not guarantee that the substance is present in the proper concentration.

We also consider claims and whether the ingredients deliver the desired results as suggested by research. Some brands may use celebrities to endorse their products. They may also include success stories that are either typical of outcomes or not.

FAQs 

What are the best nootropics for sleep?

The best nootropics for sleep are the ones that help promote relaxation, reduce stress and anxiety, and improve sleep quality without causing drowsiness or grogginess the next day.

One of the top nootropics for sleep is NooCube. It’s caffeine, gluten, and non-GMO. It’s designed to reduce sleep deprivation, stimulate the brain, and reduce stress and anxiety by using the right amounts of tried-and-trusted ingredients.

Do nootropics increase REM sleep?

Yes, nootropics increase REM sleep because they can block the synthesis of norepinephrine, which can decrease REM sleep.

Can nootropics help you sleep better?

Nootropics can help you maintain a regular circadian cycle and encourage restful sleep. They can also increase focus and concentration, relax your body, give you more energy, and help you fall and stay asleep.

A Word From Our Medical Team

While nootropic supplements can help treat sleep disorders and improve sleep quality, it’s important to incorporate other good practices into your routine before supplementing.

For example, regular exercise has a positive effect on the quality of sleep. Jogging for 60 minutes 4–5 times per week over an 8–12-week period can help improve insomnia.

Try to have consistency in your sleeping patterns. An irregular sleeping cycle disrupts the circadian rhythm, which can interfere with your sleep stages.

The circadian rhythm is a collection of 24-hour-cycled behavioral, physiological, and mental changes. The circadian rhythm’s main job is to determine whether the body is prepared for sleep.

To support healthy sleep, try to keep the room as dark as possible when going to bed. The circadian rhythm, which helps the brain and body determine when it’s dark, can also be influenced by cues like light.

Conclusion

Adequate sleep is just as essential as eating a balanced diet and exercising frequently.

However, many people have trouble falling asleep; they wake up frequently or are not well-rested when they wake up. This can be challenging to keep your health and well-being at their best.

Nootropic sleep supplements like NooCube Sleep Upgrade, Mind Lab Pro, and Performance Lab Sleep can offer a healthy and secure solution to reduce sleep deprivation without causing negative side effects. Nootropics are also calming and relaxing and can help improve cognitive function the next day.

Before taking any sleep supplement, try implementing healthy sleep habits into your routine, such as having a consistent sleep cycle and exercising regularly.  

Nootropic supplements are one strategy to boost the likelihood of having a good night’s sleep, but they’re likely to be most helpful when combined with healthy sleeping habits and routines.

Written by Donika Vata, MD
Dr. Donika Vata is a highly accomplished MD whose extensive experience in the healthcare industry spans over 5 years, making her a distinguished Medical Writer and Researcher for the esteemed Health Reporter. Notably, she also holds the role of a General Practice Doctor and has rendered her exceptional patient care services in various clinics worldwide.
The article was fact checked by Edna Skopljak, MD
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Dr. Donika Vata
Written by Donika Vata, MD
HR_author_photo_Edna
Fact checked by Edna Skopljak, MD
Last update: January 3, 2024
9 min read 1012 Views 0 Reviews
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