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Home arrow Health arrow Mental Health arrow 7 Best Nootropics for Anxiety: Find Calm Now

7 Best Nootropics for Anxiety: Find Calm Now

HR_author_photo_Edna
Written by Edna Skopljak, MD
Dr. Donika Vata
Fact checked by Donika Vata, MD
Last update: October 13, 2023
8 min read 766 Views 0 Reviews
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Struggling with anxiety? Nootropics could be your solution

best nootropics for anxiety

How do we vet brands and products? Learn more.

Many US adults experience some form of anxiety in their lives, from generalized and social anxiety to post-traumatic stress disorder. Anxiety can affect our quality of life, sleep quality, and brain health. But there is an answer to these effects.

Nootropics are smart drugs that improve cognitive function and cross the blood-brain barrier to improve wellness. Currently, there are numerous nootropics on the market, so selecting the most suitable option can be difficult.

To ensure you make the best decision when choosing nootropics for anxiety disorders, we have gathered the key facts on the top 7 options for improving your mental health. 

#1 Best for Anxiety star
Noocube Logo
4.5
stars
  • Reduces “brain overwhelm” feelings
  • Benefit those with generalized anxiety disorder
  • Decreases stress levels
  • Minimizes brain fog and fatigue
  • Leads to a calmer disposition and a better mood
Learn More
Buy Now
#2
xanapril logo
4.4
stars
  • Ideal for daily use
  • Effective as a sleep aid
  • Manages anxiety triggers
  • Helps to deal with social anxiety
Learn More
Learn More
#3
vyvamind logo
4.4
stars
  • Helps to manage stressful situations
  • Promotes relaxation
  • Boosts mental clarity
  • Protects brain cells
Learn More
Learn More

Top 7 Best Nootropics for Anxiety: Overview

An estimated 31.1% of US adults have to deal with anxiety symptoms, which can cause high blood pressure and mood swings. However, many nootropic options can counter this – they can elevate mood and enhance cognitive functions.

Discover the 7 best nootropics below and find out each product’s pros, cons, and best features.

#1 NooCube: Best overall

Noocube Logo
Our rating:
4.5
stars
  • Reduces “brain overwhelm” feelings
  • Decreases stress levels
  • Minimizes brain fog and fatigue
  • Leads to a calmer disposition and a better mood
Visit NooCube

NooCube is a nootropic formula that manufacturers created specifically for people who show signs of anxiety and stress. The all-in-one solution contains an amino acid and herbal ingredient combination, including bacopa monnieri and an award-winning blend of carotenoids called Lutemax.

Studies show that the amino acid compounds in NooCube can reduce chronic anxiety and stress by decreasing cortisol. Many herbs, such as bacopa monnieri, also reduce cortisol levels in the body, therefore it helps for those with social anxiety.

As well as powerful antioxidants found in green tea, which are useful for patients with stress-induced disorders like anxiety, NooCube contains B vitamins that contribute to a positive mood. This combination can decrease the body’s stress response and lead to effective stress relief.

Another key ingredient of NooCube, L-tyrosine, can alleviate stress, treat symptoms, and reduce anxiety by regulating key neurotransmitters. This formula can improve mood as its ingredients also support dopamine.

An advantage of NooCube is that the formula does not contain caffeine. However, it may take up to 30 days to notice this solution’s effects.

Pros
  • checkmark
    Caffeine-free blend of ingredients
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    Money-back guarantee for 60 days
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    Clinically proven, natural ingredients
Cons
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    May cause mild stomach upset

#2 Xanapril: Best for reducing stress

xanapril logo
Our rating:
4.4
stars
  • Great for reducing social anxiety
  • Ideal for daily use
  • Effective as a sleep aid
  • Manages anxiety triggers
Learn More

Xanapril’s one-of-a-kind formula is an anti-stress solution that boosts positivity and happiness. Its manufacturers state that this nootropic helps patients manage anxiety triggers, sleep better, and feel calmer during high-stress situations.

Xanapril’s ingredients include ashwagandha, which studies show can reduce stress and relieve anxiety by reducing cortisol and DHEA-S. It also contains magnesium, which reduces adrenocorticotropic hormones and cortisol levels and reduces anxiety.

This formula’s gamma-aminobutyric acid, or GABA, reduces the effects of anxiety disorder as well. Studies suggest this compound inhibits neurotransmitters to achieve this outcome and reduce depression symptoms.

Xanapril is an over-the-counter solution for which you will not require a doctor’s prescription. However, the formula may cause headaches for some people.

Pros
  • checkmark
    Fast acting formula
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    Helps to deal with social anxiety
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    Clinically safe, natural ingredients
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    Manufactured in an FDA-inspected facility
Cons
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    May cause headaches

#3 Vyvamind: Best for relaxation

vyvamind logo
Our rating:
4.4
stars
  • Helps to manage stressful situations and reduce social anxiety
  • Promotes relaxation
  • Boosts mental clarity
  • Improves brain function
  • Protects brain cells
Learn More

Manufacturers of the Vyvamind solution aim to support students, traders, and workers to manage mentally demanding, high-stress situations. The ingredients of Vyvamind include B vitamins and the L-theanine, which support a healthy immune system and reduce trait anxiety scores, respectively.

The formula’s L-theanine promotes relaxation, boosts mental clarity by reducing neurotransmitters’ impact, and enhances alpha brain waves. It also protects brain cells from damage and might benefit those with GAD (generalized anxiety disorder).

Vyvamind’s ingredients are specially selected, safe, and clinically proven to be effective in treating anxiety based on extensive research.

An advantage of this formula, like many best nootropic brands, is that it is FDA-compliant and does not require a prescription to receive it. However, it does contain caffeine, which can cause anxiety symptoms.

Pros
  • checkmark
    Clinically proven ingredients
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    Soy-free solution
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    Non-GMO capsules
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    Manufactured in FDA-registered facilities
Cons
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    Contains caffeine

#4 Mind Lab Pro: Best for cognitive function

mind lab pro logo
Our rating:
4.4
stars
  • Targets a variety of cognitive functions
  • Boosts mood
  • Reduces brain fog
Learn More

Since 2015, manufacturers at Mind Lab Pro have been working on smart drugs such as the Mind Lab Pro nootropic. They have completed placebo-controlled trials to determine the effectiveness of their product and claim that it reduces brain fog and anxiety.

With 11 nootropic ingredients that caused improved cognitive function and lowered anxiety levels, Mind Lab Pro can improve mental health. As well as Rhodiola rosea and L-theanine, this formula contains bacopa monnieri, which studies suggest lowers anxiety.

The Mind Lab Pro packaging clearly shows each of the 11 ingredients’ doses, so you will always know which compounds you consume. With the recommended 2–4 daily capsules, the manufacturers suggest the nootropic supplement takes effect within 30 minutes.

Mind Lab Pro claims that their nootropic does not have negative side effects and that 2 capsules per day work against mental fatigue. The product also enhances brain function due to the proanthocyanidin antioxidants, which reduce brain oxidative stress. However, this nootropic may interfere with your medications.

Pros
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    Vegan-friendly formula
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    Free from GMOs
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    Capsules undergo quality tests
Cons
  • checkmark
    Free samples unavailable
  • checkmark
    May interfere with your medications

#5 Nooceptin: Best for improving mood

nooceptin logo
Our rating:
4.2
stars
  • Reduces stress and relieves anxiety
  • Improves mood and motivation
  • Protects brain cells
Learn More

Nooceptin’s unique blend of neurochemicals has several benefits for health. It eliminates brain fog, increases your concentration levels without caffeine, and is ideal as a stress and anxiety solution. This all-in-one nootropic requires you to take 2 capsules daily for a clearer, less anxious mind.

The formula includes ingredients such as L-theanine, ginseng extract, and bacopa monnieri, promoting calmness. Ginseng has been proven to suppress hormonal changes caused by stress, and L-theanine effectively reduces stress-related symptoms by regulating the brain’s neurotransmitters.

With Nooceptin, you can also target the physiological cause of your anxiety, high cortisol levels, and increase your brain’s defenses against anxiety. Its adaptogens are responsible for this, enhancing the endocrine balance between the adrenal and pituitary glands.

Nooceptin contains Rhodiola rosea extract, which decreases cortisol. This function also leads to fewer feelings of stress. However, it is an expensive nootropic.

Pros
  • checkmark
    Science-backed ingredients
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    Multi-buy savings
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    Fast product shipping
Cons
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    May take 6 weeks to take effect

#6 Performance Lab Mind: Best for mental performance

Performance Lab Mind logo
Our rating:
4.2
stars
  • Promotes cognitive health
  • Protects brain health
  • Prevents burnout
  • Handles short-term stress
Learn More

One key advantage of Performance Lab Mind’s nootropic is that it fights stress burnout and supports brain health. Manufacturers suggest that you can benefit from its ingredients that fight anxiety with 1–2 capsules daily.

This formula contains phosphatidylserine and L-tyrosine. Phosphatidylserine can blunt cortisol’s effects on athletes, reducing stress.

The nootropic’s L-tyrosine contributes to brain chemical production. When consumed in Performance Lab Mind’s nootropic formula, it reverses cognitive decline that can be caused by chronic stress – especially when neurotransmitter functions are impaired. 

This ingredient is, therefore, ideal for handling short-term stressful situations or social anxiety.

If you experience brain fog, Performance Lab Mind can also help prevent this by reducing the depletion of catecholamines, hormones that are released in response to physical or emotional stress. However, this formula can interact with other medications.

Pros
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    30-day product guarantee
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    Offers nutrients missing from a diet
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    Caffeine-free capsules
Cons
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    May interact with other medications
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    Unavailable in some locations

#7 Brain Pill: Best for fighting brain fog

brainpill logo
Our rating:
4.0
stars
  • Scientifically proven ingredients for stress
  • Ideal for stress and anxiety disorder
  • Can improve sleep quality
Learn More

Brain Pill is an anti-stress supplement that aids sleep quality, increases energy levels, and reduces anxiety (social anxiety included). Manufacturers designed it to help people improve memory and concentration, particularly when working long hours or in stressful environments.

The formula’s manufacturers also claim that it reduces brain fog and helps people sustain cognitive energy.

To help you handle the effects of a fast-paced world, Brain Pill’s manufacturers use several key ingredients in their nootropic. The formula contains a blend of B vitamins, L-theanine, and tyrosine, which can reduce anxiety by regulating neurotransmitters, modulating alpha activity, and reversing stress-related cognitive decline.

Scientific studies back Brain Pill and show that the formula increases alertness and maintains your brain’s cellular function. However, this formula is not suitable for pregnant women and may take 30 days to take effect.

Pros
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    Doesn’t contain caffeine
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    Suitable for people of all ages (except pregnant women)
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    Medically reviewed formula
Cons
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    May take at least 30 days to take effect
  • checkmark
    Pregnant women cannot use it

Comparison Table

Comparison Winner: NooCube
4.5
stars
4.4
stars
4.4
stars
4.4
stars
4.2
stars
4.2
stars
4.0
stars
Brand
NooCube
Xanapril
Vyvamind
Mind Lab Pro
Nooceptin
Performance Lab Mind
Brain Pill
Pros

Caffeine-free

Available with a money-back guarantee (60 days)

Clinically proven ingredients

Fast-acting formula

Clinically safe, natural ingredients

Made in an FDA-inspected facility

Clinically proven ingredients

Soy-free solutionNon-GMO capsules

Manufactured in FDA-registered facilities

Vegan friendly

Free from GMOs

Undergoes quality tests

Science-backed ingredients

Multi-buy savings

Fast product shipping

Caffeine-free

Provides many nutrients

Offers a 30-day guarantee

Doesn’t contain caffeine

Formula is medically reviewed

Ideal for people of any age except pregnant women

Cons

May cause mild stomach upset

May cause headaches

Contains caffeine

Free samples unavailable

May interact with your medications

May take 6 weeks to take effect

Unavailable in some locations

May interact with your medications

May take 30 days to take effect

Pregnant women cannot use this

How to Choose the Best Nootropics for Dealing With Anxiety

Before investing in any nootropics, evaluating them against a few crucial factors is essential. We have assessed these nootropics for their quality, price, brand reputation, and effectiveness. Continue reading to find out how to choose the best formula for you.

Quality

Every nootropic we evaluated contains natural, science-backed ingredients that are top quality. Not only do many of the ingredients have anxiolytic (anxiety-reducing) effects, but the herbs, amino acids, and vitamins have other health benefits, too. Their quality can improve sleep, enhance focus, and reduce stress.

The best nootropic brand facilities will also be quality-inspected and FDA-approved, which is extra evidence of the product’s quality.

Price

For this list of quality nootropics, we looked at the quality-price ratio to determine if the prices were suitable. Although some nootropics can be costly, many are high-quality solutions for anxiety symptoms, and the quality justifies the price.

We also checked whether the nootropics provide saving opportunities through multi-buy deals. Some nootropics available also help consumers save money when they subscribe. This option ensures you get the best quality nootropics for the optimum price.

Brand reputation

When choosing a nootropic, brand reputation is a crucial factor. In many cases, the better the brand reputation, the higher the quality of the nootropic supplement.

It’s important to consider whether the brand displays the ingredients clearly on the packaging so you know which vitamins, minerals, and herbs you are putting into your body. The brands with the best reputation will be willing to share the quality of their ingredients. They will also share the dose of each.

Alongside this transparency, the best brands will offer helpful customer service or even money-back guarantees to ensure you are satisfied and can receive the necessary assistance.

Effectiveness

Although many brands suggest that their product is the best on the market, investigating these claims is essential. We looked at clinical studies into each ingredient within the nootropics to ensure that they truly help users and can provide the desired effects. 

FAQs

Do nootropics work for anxiety?

Yes. Numerous nootropics promote relaxation, tranquility, and alertness. Several studies have shown that they can reduce anxiety and improve mood when taken regularly.

What are the nootropics for stress management?

A few examples of the best nootropics for stress management include Xanapril and Vyvamind, which are effective stress reducers due to their quality ingredients, such as ashwagandha and L-theanine.

How can nootropics help with stress?

Nootropics that include ashwagandha, L-theanine, and bacopa monnieri can help with stress. The adaptogen herb ashwagandha reduces cortisol. The amino acid L-theanine reduces stress responses in the nervous system, and bacopa monnieri also decreases cortisol levels.

A Word From Our Medical Team

Nootropics can be effective in helping you reduce your anxiety symptoms, feel less stressed, and improve your sleep quality.

Not only can they adjust alpha brain waves, but they can moderate neurotransmitters and reduce cortisol. Many nootropic ingredients reduce the fight-or-flight response and make us feel calmer.

Despite the advantages of nootropics, completing other activities to reduce unpleasant anxiety symptoms is essential. Try calming anxiety at night by using breathing techniques and relieving intense anxiety during the day using the 3-3-3 rule.

It’s also crucial to eat a balanced diet and get sufficient exercise by walking or cycling. Remember that adults require 150 minutes of moderate-intensity activity, so commit to a routine to reduce your anxiety.

Don’t forget that nootropic formulas can affect other medications you may be taking. Therefore, we recommend you consult with your doctor before starting these supplements and always follow the recommended dose on the packaging to avoid side effects.

Conclusion

Nootropics can improve your overall brain health and greatly reduce anxiety. They are useful for high-stress situations and can help you avoid feeling overwhelmed.

For the best effects, always select nootropics with high-quality, science-backed, natural ingredients, such as NooCube, Xanapril, and Vyvamind.

Always remember to seek your doctor’s advice before taking any supplements.

Written by Edna Skopljak, MD
Edna Skopljak, MD, is a medical advisor for the Health Reporter, a general practitioner who also worked as a medical doctor at the Department of Orthopedic Surgery and Traumatology. In addition to clinical work, she has years of experience in medical research as an editor at a prestigious medical journal.
The article was fact checked by Donika Vata, MD
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HR_author_photo_Edna
Written by Edna Skopljak, MD
Dr. Donika Vata
Fact checked by Donika Vata, MD
Last update: October 13, 2023
8 min read 766 Views 0 Reviews
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